Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374988 | 0.82 | LTA4H (0.35) | LTA4H | |
| SCHEMBL21070040 | 0.82 | LTA4H (0.35) | LTA4H | |
| SCHEMBL17814865 | 0.77 | LTA4H (0.36) | LTA4HTP53 | |
| SCHEMBL14753764 | 0.76 | FFAR3 (0.36) | LTA4HTP53ALDH1A1TDP1 | |
| SCHEMBL11163798 | 0.76 | FFAR3 (0.36) | LTA4HTP53ALDH1A1TDP1 | |
| SCHEMBL2597884 | 0.73 | CYP2D6 (0.39) | CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL25409530 | 0.73 | KMT2A (0.55) | CYP2D6CYP2C19ALDH1A1MAPT | |
| SCHEMBL25409526 | 0.73 | KMT2A (0.55) | CYP2D6CYP2C19ALDH1A1MAPT | |
| SCHEMBL9303262 | 0.72 | ALDH1A1 (0.40) | LTA4HTP53ALDH1A1LMNA | |
| SCHEMBL8990012 | 0.72 | TSHR (0.33) | LTA4HTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023057813-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |
| WO-2023057814-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |