Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11163798 | 0.81 | FFAR3 (0.36) | LTA4HALDH1A1TP53 | |
| SCHEMBL14753764 | 0.81 | FFAR3 (0.36) | LTA4HALDH1A1TP53 | |
| SCHEMBL1563864 | 0.78 | — | — | |
| SCHEMBL31589933 | 0.78 | CHRNB2 (0.35) | ALDH1A1 | |
| SCHEMBL11166642 | 0.77 | LTA4H (0.40) | LTA4HALDH1A1TP53 | |
| SCHEMBL9303262 | 0.77 | ALDH1A1 (0.40) | TSHRLTA4HALDH1A1TP53 | |
| SCHEMBL9302554 | 0.77 | ALDH1A1 (0.40) | TSHRLTA4HALDH1A1TP53 | |
| SCHEMBL17814865 | 0.77 | LTA4H (0.36) | LTA4HTP53 | |
| SCHEMBL31589523 | 0.77 | KDM4C (0.36) | ALDH1A1 | |
| SCHEMBL16006838 | 0.74 | FOLH1 (0.32) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578633-A | VASOPRESSIN AND OXYTOCIN ANTAGONISTS | SANOFI (FR) | 1996-11-26 | — | — | US | disclosed |
| US-5481005-A | N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present | SANOFI (FR) | 1996-01-02 | — | — | US | disclosed |
| US-5397801-A | Affinity for vasopressin and ocytocin receptors; disorders of nervous, cardiovascular and gastrointestinal systems | SANOFI (FR) | 1995-03-14 | — | — | US | disclosed |
| US-5338755-A | Have affinity for vasopressin and ocytocin receptors; intermediates for drugs that act on central nervous system | ELF SANOFI (FR) | 1994-08-16 | — | — | US | disclosed |