Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11163798 | 0.81 | FFAR3 (0.36) | LTA4HGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL14753764 | 0.81 | FFAR3 (0.36) | LTA4HGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21070040 | 0.78 | LTA4H (0.35) | LTA4H | |
| SCHEMBL29374988 | 0.78 | LTA4H (0.35) | LTA4H | |
| SCHEMBL9302554 | 0.77 | ALDH1A1 (0.40) | LTA4HTP53 | |
| SCHEMBL8990012 | 0.77 | TSHR (0.33) | LTA4HTP53 | |
| SCHEMBL11166642 | 0.77 | LTA4H (0.40) | LTA4HTP53 | |
| SCHEMBL9303262 | 0.77 | ALDH1A1 (0.40) | LTA4HTP53 | |
| SCHEMBL25129442 | 0.77 | CYP2D6 (0.40) | LTA4HTP53 | |
| SCHEMBL16092923 | 0.75 | KDM4A (0.34) | LTA4HKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016090157-A1 | BIOMOLECULE CONJUGATES | CELGENE CORPORATION (US) | 2016-06-09 | — | — | WO | disclosed |