Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 3/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 6/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25129545 | 0.89 | ALDH1A1 (0.37) | NOD1ALDH1A1EPHX1ALBFOLH1 | |
| SCHEMBL23604792 | 0.86 | NMT1 (0.45) | NOD1FOLH1NMT2NMT1 | |
| SCHEMBL19062765 | 0.85 | NMT1 (0.49) | NOD1GLP1RNMT2NMT1 | |
| SCHEMBL25129822 | 0.84 | NMT2 (0.44) | NOD1ALDH1A1GLP1RNMT2NMT1 | |
| SCHEMBL24235520 | 0.84 | NOD1 (0.40) | NOD1EPHX2ALDH1A1ALBFOLH1 | |
| SCHEMBL16231541 | 0.83 | FOLH1 (0.40) | NOD1EPHX2ALDH1A1ALBFOLH1 | |
| SCHEMBL22692615 | 0.81 | NMT2 (0.47) | NOD1EPHX2GLP1RNMT2NMT1 | |
| SCHEMBL24239462 | 0.80 | ALB (0.44) | NOD1EPHX2ALBGLP1RNMT2 | |
| SCHEMBL16231542 | 0.80 | FOLH1 (0.38) | NOD1EPHX2ALDH1A1ALBFOLH1 | |
| SCHEMBL29299599 | 0.80 | ALDH1A1 (0.44) | ALDH1A1EPHX1CASP2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023057812-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDER | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |
| WO-2023057814-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |
| WO-2023057813-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |