Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MMP14 | P50281 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27167409 | 0.83 | POLB (0.36) | KDM4EHSP90AA1KMT2AMAPTMMP14 | |
| SCHEMBL25130855 | 0.81 | CSNK2A1 (0.34) | KDM4EHSP90AA1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL27167395 | 0.79 | PDE10A (0.34) | KDM4EKMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL31700880 | 0.76 | MTNR1A (0.37) | KDM4EHSP90AA1KMT2AMAPTHTT | |
| SCHEMBL31729196 | 0.76 | CCR4 (0.33) | KDM4EMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL26639820 | 0.76 | MEN1 (0.34) | KDM4EKMT2AMAPTMEN1LMNA | |
| SCHEMBL30657478 | 0.76 | MEN1 (0.34) | KDM4EKMT2AMAPTMEN1LMNA | |
| SCHEMBL26639901 | 0.72 | ALDH1A1 (0.43) | KDM4EKMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL30666114 | 0.69 | HSP90AA1 (0.38) | KDM4EHSP90AA1KMT2AMAPTMMP14 | |
| SCHEMBL26656462 | 0.69 | HSP90AA1 (0.38) | KDM4EHSP90AA1KMT2AMAPTMMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023051628-A1 | SOS1 INHIBITORS HAVING PYRIDO SIX-MEMBERED RING STRUCTURE | 上海海和药物研究开发股份有限公司 | 2023-04-06 | — | — | WO | disclosed |