Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26639820 | 1.00 | MEN1 (0.34) | MEN1KMT2AALDH1A1MAPTPDE5A | |
| SCHEMBL26639901 | 0.83 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1MAPTPDE5A | |
| SCHEMBL30657485 | 0.81 | MEN1 (0.34) | MEN1KMT2AMAPTPDE5A | |
| SCHEMBL26639760 | 0.81 | MEN1 (0.34) | MEN1KMT2AMAPTPDE5A | |
| SCHEMBL29766212 | 0.78 | ALDH1A1 (0.32) | KMT2AALDH1A1LMNA | |
| SCHEMBL21196225 | 0.78 | ALDH1A1 (0.32) | KMT2AALDH1A1LMNA | |
| SCHEMBL25130861 | 0.76 | KDM4E (0.35) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL31729196 | 0.74 | CCR4 (0.33) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| SCHEMBL30657462 | 0.72 | HRH4 (0.41) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL26639919 | 0.72 | HRH4 (0.41) | MEN1KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215256-A1 | SOS1 INHIBITORS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2023-11-09 | — | — | WO | disclosed |