Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.36 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327464 | 0.84 | EPHX1 (0.47) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| Hydrochloric Acid SCHEMBL23533426 | 0.82 | GNAO1 (0.47) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL23533551 | 0.82 | KCNH2 (0.51) | — | |
| Hydrochloric Acid SCHEMBL29966132 | 0.81 | GNAO1 (0.53) | CHRM1 | |
| SCHEMBL31072452 | 0.79 | PRMT3 (0.49) | CHRM3SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL13934478 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2DRD2MEN1KMT2AHTR4 | |
| SCHEMBL3950912 | 0.79 | CHRM1 (0.40) | CYP1A2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3424498 | 0.78 | ACHE (0.44) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL14012818 | 0.77 | HRH3 (0.46) | CYP1A2MAPK1SMN1; SMN2DRD2 | |
| SCHEMBL3424285 | 0.76 | ACHE (0.48) | CYP1A2CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023053016-A1 | IONIZABLE CATIONIC COMPOUND | Seqirus Inc. (US) | 2023-04-06 | — | — | WO | disclosed |