Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24939113 | 0.79 | CTSV (0.37) | CTSLCTSBCTSSCTSK | |
| SCHEMBL23847805 | 0.71 | MAPT (0.34) | CTSLCAPN1 | |
| SCHEMBL4370243 | 0.71 | CAPN1 (0.32) | CTSLCAPN1 | |
| SCHEMBL25134614 | 0.71 | PTGER3 (0.35) | — | |
| SCHEMBL6732243 | 0.70 | AR (0.44) | CTSLCAPN1 | |
| SCHEMBL24740339 | 0.70 | CTSL (0.33) | CTSLCAPN1CTSBCTSSCTSK | |
| Hydrochloric Acid SCHEMBL4188440 | 0.70 | CAPN1 (0.31) | CTSLCAPN1 | |
| SCHEMBL25006853 | 0.70 | PTGER3 (0.34) | — | |
| SCHEMBL24690796 | 0.69 | CCR2 (0.34) | — | |
| SCHEMBL30396609 | 0.69 | CTSL (0.36) | CTSLCAPN1CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023055702-A1 | MAIN PROTEASE (M PRO) INHIBITORS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2023-04-06 | — | — | WO | disclosed |