SCHEMBL25137342

SCHEMBL25137342

Cc1ccc2c(c1)N(C)C(c1ccccc1)(c1ccccc1)N2C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
ALDH1A1 P00352 3/20 0.46
GAA P10253 2/20 0.46
MCL1 Q07820 2/20 0.46
PAX8 Q06710 1/20 0.46
KMT2A Q03164 5/20 0.38
MEN1 O00255 4/20 0.38
MAPT P10636 4/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
THRB P10828 1/20 0.38
MPI P34949 1/20 0.38
HTT P42858 1/20 0.38
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP3A4 P08684 1/20 0.36
CRHBP P24387 1/20 0.36
ATM Q13315 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25137469 0.75 FGFR1 (0.35) LMNAL3MBTL1ALDH1A1GAAMCL1
SCHEMBL25137336 0.74 KDM4E (0.42) LMNAL3MBTL1ALDH1A1GAAMCL1
SCHEMBL24885423 0.73 L3MBTL1 (0.35) LMNAL3MBTL1ALDH1A1GAAMCL1
SCHEMBL25137406 0.69 ALDH1A1 (0.44) LMNAL3MBTL1ALDH1A1GAAMCL1
SCHEMBL25137348 0.68 KDM4E (0.37) ALDH1A1GAAKMT2AMEN1MAPT
SCHEMBL12901940 0.67 MAOA (0.43) LMNAL3MBTL1GAAKMT2AMEN1
SCHEMBL25137345 0.67 KDM4E (0.39) ALDH1A1GAAKMT2AMAPTKDM4E
SCHEMBL26446479 0.64 SMN1; SMN2 (0.38) LMNAL3MBTL1ALDH1A1GAAMCL1
SCHEMBL1612154 0.64 ALDH1A1 (0.42) LMNAL3MBTL1ALDH1A1GAAKMT2A
SCHEMBL1611442 0.64 ALDH1A1 (0.42) LMNAL3MBTL1ALDH1A1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP LMNA 2541/4885L3MBTL1 1668/4885ALDH1A1 658/4885
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP LMNA 2541/4885L3MBTL1 1668/4885ALDH1A1 658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.