SCHEMBL25137336

SCHEMBL25137336

Cc1ccc2c(c1)N(C)C(C)(C)N2C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 3/20 0.42
GAA P10253 3/20 0.42
MAPT P10636 2/20 0.42
HSD17B10 Q99714 2/20 0.42
NSD2 O96028 1/20 0.42
APP P05067 1/20 0.42
HPGD P15428 1/20 0.42
SNCA P37840 1/20 0.42
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
GFER P55789 1/20 0.41
HKDC1 Q2TB90 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
HTT P42858 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25137348 0.75 KDM4E (0.37) KDM4EALDH1A1GAAMAPTHSD17B10
SCHEMBL25137342 0.74 LMNA (0.46) KDM4EALDH1A1GAAMAPTKMT2A
SCHEMBL25137345 0.74 KDM4E (0.39) KDM4EALDH1A1GAAMAPTHSD17B10
SCHEMBL4624622 0.70 TERT (0.41) KDM4EALDH1A1MAPTHSD17B10KMT2A
SCHEMBL17339860 0.70 TERT (0.41) KDM4EALDH1A1MAPTHSD17B10KMT2A
SCHEMBL12610469 0.70 MEN1 (0.38) KDM4EALDH1A1GAAMAPTKMT2A
SCHEMBL5023395 0.67 ALDH1A1 (0.44) KDM4EALDH1A1GAAMAPTHSD17B10
SCHEMBL29033541 0.67 ALDH1A1 (0.47) KDM4EALDH1A1GAAMAPTHTT
SCHEMBL27130393 0.67 HTT (0.34) KDM4EALDH1A1GAAMAPTHSD17B10
SCHEMBL27130396 0.67 KDM4E (0.37) KDM4EALDH1A1GAAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP KDM4E 4314/4885ALDH1A1 658/4885GAA 2849/4885
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP KDM4E 4314/4885ALDH1A1 658/4885GAA 2849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.