Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931433 | 0.91 | LMNA (0.34) | ALDH1A1TP53TSHR | |
| SCHEMBL2515971 | 0.77 | ALDH1A1 (0.32) | ALDH1A1TP53TSHR | |
| SCHEMBL2516026 | 0.73 | PRKCA (0.31) | — | |
| SCHEMBL24082887 | 0.72 | — | — | |
| SCHEMBL3371080 | 0.70 | — | — | |
| SCHEMBL28240807 | 0.68 | TSHR (0.36) | ALDH1A1TP53TSHR | |
| SCHEMBL11005864 | 0.67 | LMNA (0.36) | ALDH1A1PGK1PGK2SLC22A6 | |
| SCHEMBL6753286 | 0.67 | LMNA (0.36) | ALDH1A1PGK1PGK2SLC22A6 | |
| SCHEMBL10787382 | 0.66 | KDM4E (0.33) | — | |
| SCHEMBL4358908 | 0.65 | MAPK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109874-A1 | INHIBITION OF GLUTATHIONE TRANSFERASE ZETA | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2011-09-15 | — | — | WO | disclosed |