Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | THRA | P10827 | 8/20 | 0.35 |
| ▸ | THRB | P10828 | 8/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4791412 | 0.93 | DNM1 (0.48) | DNM1ALDH1A1THRATHRBCES2 | |
| SCHEMBL170759 | 0.93 | DNM1 (0.48) | DNM1ALDH1A1THRATHRBCES2 | |
| SCHEMBL19034541 | 0.85 | DNM1 (0.36) | DNM1ALDH1A1THRATHRBTSHR | |
| SCHEMBL25147997 | 0.84 | ALDH1A1 (0.38) | DNM1ALDH1A1THRATHRBCES2 | |
| SCHEMBL4244087 | 0.82 | CES1 (0.47) | ALDH1A1THRBCES2CES1TSHR | |
| SCHEMBL19085564 | 0.81 | DNM1 (0.44) | DNM1ALDH1A1TSHRMAPT | |
| Ammonia Solution, Strong SCHEMBL2638345 | 0.79 | CES1 (0.45) | ALDH1A1THRBCES2CES1TSHR | |
| SCHEMBL23655783 | 0.77 | — | — | |
| SCHEMBL3810882 | 0.76 | — | — | |
| SCHEMBL22711835 | 0.76 | CES2 (0.48) | ALDH1A1CES2CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608308-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | Novartis AG (CH) | 2020-02-12 | — | — | EP | disclosed |