Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | CTSD | P07339 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964113 | 0.85 | POLB (0.64) | SMN1; SMN2USP2CTSDCTSLCTSB | |
| SCHEMBL9158848 | 0.84 | HPGD (0.42) | SMN1; SMN2USP2CTSDCTSLCTSB | |
| SCHEMBL7275713 | 0.82 | GLA (0.69) | SMN1; SMN2GLAL3MBTL1TSHRPOLB | |
| SCHEMBL19478687 | 0.81 | GLA (0.68) | SMN1; SMN2USP2CTSDCTSLCTSB | |
| SCHEMBL4613472 | 0.79 | ALDH1A1 (0.58) | SMN1; SMN2USP2CTSDCTSLCTSB | |
| SCHEMBL25148205 | 0.77 | POLB (0.55) | SMN1; SMN2USP2CTSDCTSLCTSB | |
| SCHEMBL3707572 | 0.77 | LMNA (0.73) | SMN1; SMN2GLAL3MBTL1TSHRPOLB | |
| SCHEMBL28292220 | 0.77 | KDM4E (0.49) | SMN1; SMN2USP2CTSDCTSLCTSB | |
| SCHEMBL3753324 | 0.77 | L3MBTL1 (0.64) | SMN1; SMN2GLAL3MBTL1TSHRPOLB | |
| SCHEMBL14226183 | 0.76 | CTSL (0.54) | SMN1; SMN2USP2CTSDCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240245699-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2024-07-25 | — | — | US | disclosed |
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | disclosed |
| US-20210290631-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2021-09-23 | — | — | US | disclosed |
| US-11058689-B2 | Pyrrole compounds, a process for their preparation and pharmaceutical | LES LABORATOIRES SERVIER (FR) | 2021-07-13 | — | — | US | disclosed |
| US-11028070-B2 | Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2021-06-08 | — | — | US | disclosed |
| US-20200261464-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2020-08-20 | — | — | US | disclosed |
| US-20200262816-A1 | ISOINDOLINE OR ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2020-08-20 | — | — | US | disclosed |
| US-10688101-B2 | Pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATORIES SERVIER (FR) | 2020-06-23 | — | — | US | disclosed |
| US-10689364-B2 | Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2020-06-23 | — | — | US | disclosed |
| US-10414754-B2 | Indolizine compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2019-09-17 | — | — | US | disclosed |
| CN-105579450-A | Novel indolizine compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2016-05-11 | — | — | CN | disclosed |
| CN-105431422-A | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2016-03-23 | — | — | CN | disclosed |
| US-20150313923-A1 | PHOSPHATE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2015-11-05 | — | — | US | disclosed |
| US-20150313907-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2015-11-05 | — | — | US | disclosed |
| US-9115159-B2 | Phosphate compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2015-08-25 | — | — | US | disclosed |
| US-9108983-B2 | Pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2015-08-18 | — | — | US | disclosed |
| CN-104341451-A | New phosphate compounds, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2015-02-11 | — | — | CN | disclosed |
| CN-104341395-A | Novel azole compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2015-02-11 | — | — | CN | disclosed |
| US-20150031648-A1 | PHOSPHATE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2015-01-29 | — | — | US | disclosed |
| US-20150031673-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2015-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11058689-B2 | Pyrrole compounds, a process for their preparation and pharmaceutical | PDCD11, RRM2B, RRS1 | SMN1; SMN2 2763/4885USP2 1998/4885CTSD 1404/4885 |
| US-20210290631-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PDCD11, RRM2, RRM2B | SMN1; SMN2 2545/4885USP2 1802/4885CTSD 1195/4885 |
| US-20150031673-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PDCD11, RRM2B, RRM2 | SMN1; SMN2 2908/4885USP2 2043/4885CTSD 1647/4885 |
| US-20200261464-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PDCD11, RRS1, RRM2B | SMN1; SMN2 2870/4885USP2 2070/4885CTSD 1608/4885 |
| US-10414754-B2 | Indolizine compounds, a process for their preparation and pharmaceutical compositions containing them | IDO1, API5, IDO2 | SMN1; SMN2 4369/4885USP2 2872/4885CTSD 1889/4885 |
| US-20240245699-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PDCD11, RRM2B, RRM2 | SMN1; SMN2 2908/4885USP2 2043/4885CTSD 1647/4885 |
| US-20200262816-A1 | ISOINDOLINE OR ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BAX, RECQL, CASP7 | SMN1; SMN2 3115/4885USP2 2808/4885CTSD 2421/4885 |
| US-10689364-B2 | Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them | BAX, CASP7, CASP3 | SMN1; SMN2 2864/4885USP2 2789/4885CTSD 2205/4885 |
| US-10688101-B2 | Pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them | PDCD11, RRM2B, RRM2 | SMN1; SMN2 2908/4885USP2 2043/4885CTSD 1647/4885 |
| US-20150313907-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PDCD11, RRM2B, RRM2 | SMN1; SMN2 2908/4885USP2 2043/4885CTSD 1647/4885 |
| US-20150313923-A1 | PHOSPHATE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ENPP2, RB1, RRM2 | SMN1; SMN2 3510/4885USP2 3237/4885CTSD 1440/4885 |
| US-20150031648-A1 | PHOSPHATE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ENPP2, RB1, RRM2 | SMN1; SMN2 3510/4885USP2 3237/4885CTSD 1440/4885 |
| US-11028070-B2 | Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them | BAX, RECQL, CASP7 | SMN1; SMN2 3115/4885USP2 2808/4885CTSD 2421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.