Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.39 |
| ▸ | PGR | P06401 | 4/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25148803 | 0.88 | NR3C1 (0.40) | POLBTDP1NR3C2PGRNR3C1 | |
| SCHEMBL25149367 | 0.88 | PDCD1 (0.42) | POLBTDP1KLKB1CD274PDCD1 | |
| SCHEMBL30364642 | 0.88 | PDCD1 (0.42) | POLBTDP1KLKB1CD274PDCD1 | |
| SCHEMBL30364609 | 0.76 | LMNA (0.41) | POLBCD274PDCD1LG2 | |
| SCHEMBL19539560 | 0.75 | POLB (0.47) | POLBTDP1NR3C2PGRNR3C1 | |
| SCHEMBL25149306 | 0.69 | PARP15 (0.42) | POLBTDP1NR3C2PGRNR3C1 | |
| SCHEMBL30364876 | 0.69 | PDCD1 (0.44) | POLBTDP1CD274PDCD1TACR3 | |
| SCHEMBL25148626 | 0.69 | PARP15 (0.42) | POLBTDP1NR3C2PGRNR3C1 | |
| SCHEMBL25148734 | 0.69 | PDCD1 (0.44) | POLBTDP1CD274PDCD1TACR3 | |
| SCHEMBL21078996 | 0.68 | TDP1 (0.68) | POLBTDP1CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023062575-A1 | CYCLIC VINYL SULFONE COMPOUNDS AS WRN INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2023-04-20 | — | — | WO | disclosed |