Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25148754 | 0.79 | KDM4E (0.40) | KDM4EGAAAPPCYP3A4CYP2D6 | |
| SCHEMBL31273368 | 0.69 | KDM4E (0.47) | KDM4EGLAGAACYP2C19HSD17B2 | |
| SCHEMBL25149262 | 0.67 | LMNA (0.44) | GAAHSD17B2 | |
| SCHEMBL25149130 | 0.66 | KDM4E (0.41) | KDM4EGLAGAA | |
| SCHEMBL31273371 | 0.66 | DAO (0.37) | KDM4EGAA | |
| SCHEMBL17844663 | 0.65 | KDM4E (0.47) | KDM4EGAA | |
| SCHEMBL25149085 | 0.65 | LMNA (0.32) | HSD17B2 | |
| SCHEMBL31422912 | 0.64 | CNR2 (0.36) | HSD17B2 | |
| SCHEMBL31423302 | 0.64 | MMP9 (0.36) | KDM4E | |
| SCHEMBL31422848 | 0.64 | CNR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023062575-A1 | CYCLIC VINYL SULFONE COMPOUNDS AS WRN INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2023-04-20 | — | — | WO | disclosed |