Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2515397 | 0.85 | KDM4E (0.47) | ATG4BKDM4EALDH1A1GAARAB9A | |
| SCHEMBL9837446 | 0.81 | KDM4E (0.39) | NPSR1KDM4EALDH1A1GAARAB9A | |
| SCHEMBL10873252 | 0.71 | RAB9A (0.47) | ATG4BNPSR1KDM4EALDH1A1GAA | |
| SCHEMBL2680073 | 0.69 | RAB9A (0.56) | ATG4BNPSR1KDM4EALDH1A1GAA | |
| SCHEMBL28585105 | 0.67 | PDE10A (0.47) | NPSR1KDM4EALDH1A1GAARAB9A | |
| SCHEMBL8655973 | 0.67 | MEN1 (0.63) | KDM4EALDH1A1GAARAB9ANPC1 | |
| SCHEMBL11359764 | 0.66 | RAB9A (0.49) | ATG4BNPSR1KDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL28608866 | 0.66 | PDE10A (0.46) | NPSR1KDM4EALDH1A1GAARAB9A | |
| SCHEMBL3859410 | 0.65 | RAB9A (0.69) | KDM4EGRM5ALDH1A1GAARAB9A | |
| SCHEMBL7029896 | 0.64 | PDE10A (0.38) | NPSR1KDM4EALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114948-B1 | INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE | ABBVIE INC (US) | 2014-06-25 | — | — | EP | disclosed |
| US-8030047-B2 | Active truncated form of the RNA polymerase of flavivirus | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2011-10-04 | — | — | US | disclosed |
| US-20100267113-A1 | ACTIVE TRUNCATED FORM OF THE RNA POLYMERASE OF FLAVIVIRUS | CENTRE NAT DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-10-21 | — | — | US | disclosed |
| US-20090221795-A1 | ACTIVE TRUNCATED FORM OF THE RNA POLYMERASE OF FLAVIVIRUS | CENTRE NAT DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-09-03 | — | — | US | disclosed |
| US-7459297-B2 | Active truncated form of the RNA polymerase of flavivirus | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS (FR) | 2008-12-02 | — | — | US | disclosed |
| US-20050048472-A1 | Active truncated form of the RNA polymerase of flavivirus | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2005-03-03 | — | — | US | disclosed |