Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2515395 | 0.81 | ATG4B (0.42) | KDM4EALDH1A1GAAPOLBRAB9A | |
| SCHEMBL2515397 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1GAAPOLBRAB9A | |
| SCHEMBL28585105 | 0.72 | PDE10A (0.47) | KDM4EALDH1A1GAAPOLBRAB9A | |
| SCHEMBL7029896 | 0.71 | PDE10A (0.38) | KDM4EALDH1A1GAAPOLBRAB9A | |
| Hydrochloric Acid SCHEMBL28608866 | 0.71 | PDE10A (0.46) | KDM4EALDH1A1GAAPOLBRAB9A | |
| SCHEMBL5435508 | 0.67 | RAB9A (0.49) | KDM4EALDH1A1GAARAB9AHSD17B10 | |
| SCHEMBL14582925 | 0.66 | PDE10A (0.44) | KDM4EALDH1A1GAARAB9ALMNA | |
| SCHEMBL7048629 | 0.66 | NCF1 (0.55) | KDM4EALDH1A1GAARAB9AHSD17B10 | |
| Hydrochloric Acid SCHEMBL28590788 | 0.65 | NCF1 (0.53) | KDM4EALDH1A1GAARAB9AHSD17B10 | |
| SCHEMBL28679814 | 0.64 | KDM4E (0.45) | KDM4EALDH1A1GAAPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3145490-A | — | — | None | — | — | JP | disclosed |
| JP-H03145490-A | (2IMIDAZOLIN2-YLAMINO) TETRAHYDROQUINOXALINE | ALLERGAN INC | 1991-06-20 | — | — | JP | disclosed |