Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037834 | 0.83 | MAPT (0.46) | MAPTAKR1C3DRD2ALDH1A1GAA | |
| SCHEMBL20644489 | 0.78 | LIPG (0.34) | LIPGCA12CA2CA9 | |
| SCHEMBL20644611 | 0.77 | MAPT (0.39) | MAPTGAA | |
| SCHEMBL20639883 | 0.76 | PPARD (0.41) | MAPTAKR1C3IGF1RCCR1ALDH1A1 | |
| SCHEMBL2723507 | 0.75 | IGF1R (0.49) | MAPTAKR1C3IGF1RDRD2DRD4 | |
| SCHEMBL25160801 | 0.71 | MAPT (0.32) | MAPT | |
| SCHEMBL9274810 | 0.71 | MAPT (0.60) | MAPTALDH1A1GAAKCNH2 | |
| SCHEMBL20639931 | 0.70 | AKR1C3 (0.39) | MAPTAKR1C3IGF1RALDH1A1GAA | |
| SCHEMBL13499301 | 0.69 | DRD2 (0.36) | MAPTDRD2SMN1; SMN2FPR2 | |
| SCHEMBL17907306 | 0.68 | FPR2 (0.39) | MAPTALDH1A1GAAFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397629-B1 | METALLOENZYME INHIBITOR COMPOUNDS | NQP 1598 LTD (KY) | 2023-04-19 | — | — | EP | disclosed |