Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20644611 | 0.81 | MAPT (0.39) | MAPTRXFP1LMNATP53 | |
| SCHEMBL25160147 | 0.71 | MAPT (0.38) | MAPT | |
| SCHEMBL20644375 | 0.69 | MAPT (0.39) | MAPTTP53 | |
| SCHEMBL25669483 | 0.68 | MGLL (0.41) | MAPTLMNATP53 | |
| SCHEMBL20644489 | 0.66 | LIPG (0.34) | — | |
| SCHEMBL25685423 | 0.64 | MAPT (0.43) | MAPTRXFP1LMNATP53 | |
| SCHEMBL20644452 | 0.64 | PPARD (0.49) | MAPT | |
| SCHEMBL7438101 | 0.63 | PDE2A (0.52) | PDE2A | |
| SCHEMBL27686738 | 0.63 | NOTUM (0.40) | MAPT | |
| SCHEMBL14889068 | 0.63 | MAPT (0.39) | MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397629-B1 | METALLOENZYME INHIBITOR COMPOUNDS | NQP 1598 LTD (KY) | 2023-04-19 | — | — | EP | disclosed |