Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30329310 | 1.00 | LOXL2 (0.37) | LOXL2LOXHRH4MGLLADAMTS4 | |
| SCHEMBL30328009 | 0.78 | TRPV4 (0.40) | PTGS2PTGS1 | |
| SCHEMBL15260015 | 0.77 | NFE2L2 (0.35) | LOXL2LOXPTGS2 | |
| SCHEMBL179263 | 0.76 | LOXL2 (0.47) | LOXL2LOXMGLLARFAAH | |
| SCHEMBL19846700 | 0.74 | LOXL2 (0.36) | LOXL2LOXMGLLARACACB | |
| SCHEMBL30124822 | 0.73 | MYC (0.35) | — | |
| SCHEMBL18855226 | 0.73 | LOXL2 (0.46) | LOXL2LOXHRH4ADAMTS4MMP13 | |
| SCHEMBL22719593 | 0.73 | ADAMTS4 (0.45) | ADAMTS4MMP13 | |
| SCHEMBL29504989 | 0.73 | ADAMTS4 (0.45) | ADAMTS4MMP13 | |
| SCHEMBL20786041 | 0.73 | LOXL2 (0.44) | LOXL2LOXMGLLARFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |