Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | OGG1 | O15527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25166602 | 0.80 | ALDH1A1 (0.34) | ALDH1A1NOS3NOS2EHMT2EHMT1 | |
| SCHEMBL12411159 | 0.70 | NOS3 (0.48) | ALDH1A1NOS3NOS2EHMT2EHMT1 | |
| SCHEMBL12499637 | 0.64 | NOS3 (0.58) | ALDH1A1NOS3NOS2EHMT2EHMT1 | |
| SCHEMBL19709381 | 0.63 | NOS3 (0.41) | ALDH1A1NOS3NOS2EHMT2EHMT1 | |
| SCHEMBL19147899 | 0.62 | — | — | |
| SCHEMBL16608839 | 0.60 | LMNA (0.46) | ALDH1A1OGG1 | |
| SCHEMBL12411171 | 0.59 | GAA (0.46) | ALDH1A1NOS3NOS2 | |
| SCHEMBL25166431 | 0.59 | HAVCR2 (0.41) | ALDH1A1EHMT2EHMT1KCNH2 | |
| SCHEMBL25166581 | 0.59 | HAVCR2 (0.43) | ALDH1A1EHMT2EHMT1KCNH2 | |
| SCHEMBL30330177 | 0.59 | HAVCR2 (0.41) | ALDH1A1EHMT2EHMT1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064586-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |