SCHEMBL251666

SCHEMBL251666

C=CCC1(CC=C)C=Cc2ccccc2N1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17372718 0.82 GAA (0.34) GAAMAPT
SCHEMBL20919991 0.80 GAA (0.38) GAAMAPT
SCHEMBL7159138 0.77 MAPT (0.45) GAAMAPT
SCHEMBL2531037 0.69 KDM4E (0.30)
SCHEMBL29789697 0.66 MAPT (0.50) GAAMAPT
SCHEMBL2255782 0.66 MAPT (0.50) GAAMAPT
SCHEMBL9293762 0.64 GAA (0.43) GAAMAPT
SCHEMBL4587067 0.63 GAA (0.42) GAAMAPT
SCHEMBL4389562 0.63 GAA (0.42) GAAMAPT
SCHEMBL9281528 0.63 GAA (0.42) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088785-B2 Therapeutic compound and treatments MEDISYN TECHNOLOGIES, INC. (US) 2012-01-03 US disclosed
US-20100137253-A1 THERAPEUTIC COMPOUND AND TREATMENTS MEDISYN TECHNOLOGIES, INC. (US) 2010-06-03 US disclosed
US-7652029-B2 Therapeutic compound and treatments MEDISYN TECHNOLOGIES, INC. (US) 2010-01-26 US disclosed
EP-1778228-A2 THERAPEUTIC COMPOUND AND TREATMENTS Medisyn Technologies, Inc. (US) 2007-05-02 EP disclosed
WO-2006010127-A2 THERAPEUTIC COMPOUND AND TREATMENTS MEDISYN TECHNOLOGIES, INC. (US) 2006-01-26 WO disclosed
US-20060014770-A1 Inhibiting cell growth including cancer such as leukemia, melanoma, cancer of non-small cell lung, colon , CNS, ovarian , renal , prostate , breast , and pancreas COUSINEAU, HENRY 2006-01-19 US disclosed
JP-2005220067-A PEST-CONTROLLING AGENT SUMITOMO CHEMICAL CO LTD 2005-08-18 JP disclosed
US-20030176314-A1 Compounds for the treatment of pain H. LUNDBECK A/S (DK) 2003-09-18 US disclosed
US-20030139431-A1 Guanidines which are agonist/antagonist ligands for neuropeptide FF (NPFF) receptors H. LUNDBECK A/S (DK) 2003-07-24 US disclosed
EP-0398904-A1 PHOTOCHEMICAL MARKING OF SUBSTRATES TRAQSON LIMITED (GB) 1990-11-28 EP disclosed
WO-1989005994-A1 PHOTOCHEMICAL MARKING OF SUBSTRATES TRAQSON LIMITED (GB) 1989-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176314-A1 Compounds for the treatment of pain NPFFR2, NPFFR1, OPRL1 GAA 3614/4885MAPT 2186/4885
US-20060014770-A1 Inhibiting cell growth including cancer such as leukemia, melanoma, cancer of non-small cell lung, colon , CNS, ovarian , renal , prostate , breast , and pancreas MCL1, MRPL37, BRDT GAA 1131/4885MAPT 1743/4885
US-20100137253-A1 THERAPEUTIC COMPOUND AND TREATMENTS MDH1, MDH2, MBOAT7 GAA 106/4885MAPT 199/4885
US-20030139431-A1 Guanidines which are agonist/antagonist ligands for neuropeptide FF (NPFF) receptors NPFFR1, NPFFR2, SSTR3 GAA 3802/4885MAPT 4577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.