Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | GPR183 | P32249 | 3/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4392112 | 0.82 | POLB (0.65) | L3MBTL3ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL522002 | 0.81 | CHRNA7 (0.61) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL2050814 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL13149732 | 0.80 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2KMT2AHPGDPOLB | |
| SCHEMBL1450519 | 0.80 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6223960 | 0.80 | HPGD (0.70) | L3MBTL3ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL25442208 | 0.79 | ALDH1A1 (0.73) | L3MBTL3ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6363456 | 0.79 | LSS (0.47) | L3MBTL3ALDH1A1MEN1KMT2AHRH3 | |
| SCHEMBL6617073 | 0.78 | HPGD (0.74) | L3MBTL3ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2041678 | 0.78 | CYP2D6 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | UNIV CALIFORNIA (US) | 2023-05-11 | — | — | US | disclosed |
| EP-4125861-A2 | PROTEIN-PROTEIN INTERACTION STABILIZERS | The Regents of the University of California (US) | 2023-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | HSPBP1, HSPA8, HSPH1 | L3MBTL3 1355/4885ALDH1A1 3889/4885SMN1; SMN2 1672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.