Isobutamben

Isobutamben

SCHEMBL25178

CC(C)COC(=O)c1ccc(N)cc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 3/20 0.65
ADRB1 P08588 3/20 0.65
ADRB3 P13945 3/20 0.65
LMNA P02545 3/20 0.65
CYP1A2 P05177 3/20 0.65
CYP3A4 P08684 3/20 0.65
MAOA P21397 2/20 0.65
SCN1A P35498 2/20 0.62
SCN2A Q99250 2/20 0.62
SCN3A Q9NY46 2/20 0.62
TSHR P16473 3/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
PDE4D Q08499 1/20 0.57
PHLPP2 Q6ZVD8 1/20 0.56
ALDH1A1 P00352 3/20 0.55
MAPT P10636 2/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
PLA2G1B P04054 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isobutamben SCHEMBL4756252 0.98 ADRB2 (0.63) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL110051 0.90 ALDH1A1 (0.64) ADRB2ADRB1ADRB3TSHRALDH1A1
SCHEMBL7027777 0.89 ADRB2 (0.65) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL27667934 0.88 ALDH1A1 (0.62) ADRB2ADRB1ADRB3TSHRALDH1A1
SCHEMBL27668055 0.88 ALDH1A1 (0.62) ADRB2ADRB1ADRB3TSHRALDH1A1
SCHEMBL27668352 0.88 ALDH1A1 (0.62) ADRB2ADRB1ADRB3TSHRALDH1A1
SCHEMBL369461 0.88 ADRB2 (0.60) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL5935394 0.87 ADRB2 (0.68) ADRB2ADRB1ADRB3LMNACYP1A2
Ammonia Solution, Strong SCHEMBL8406147 0.87 ADRB2 (0.63) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL16930807 0.85 ALDH1A1 (0.55) ADRB2ADRB1ADRB3LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2416 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106952-A1 METHODS FOR TREATING CONGENITAL DISORDERS OF GLYCOSYLATION CDG CARE (US) 2026-05-21 WO claimed
US-12606641-B2 Amphiphilic carbohydrate compounds NANOMERICS LTD (GB) 2026-04-21 US claimed
WO-2025235864-A1 COATED NEEDLE ADMINISTRATION SYSTEMS EVOLUS, INC. (US) 2025-11-13 WO claimed
US-12329856-B2 Crosslinked hyaluronic acid composition with local anesthetics BIOPOLIMERI S.R.L. (IT) 2025-06-17 US claimed
US-20250186364-A1 COMBINATION OF ANTISPASMODIC AND ANESTHETIC AGENTS FOR TOPICAL PRODUCTS AND THEIR METHOD OF USE PRIMA INNOVATIONS, LLC 2025-06-12 US claimed
EP-4362994-B1 CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS BIOPOLIMERI S R L (IT) 2025-03-12 EP claimed
EP-4153640-B1 AMPHIPHILIC CARBOHYDRATE COMPOUNDS NANOMERICS LTD (GB) 2024-12-25 EP claimed
EP-3703802-B9 NASAL DELIVERY DEVICES AND METHODS OF USE THEREOF CLEXIO BIOSCIENCES LTD (IL) 2024-12-04 EP claimed
EP-3703802-B1 NASAL DELIVERY DEVICES AND METHODS OF USE THEREOF CLEXIO BIOSCIENCES LTD (IL) 2024-10-16 EP claimed
CN-118750578-A Composition for removing neck wrinkles and preparation method and application thereof 渼颜空间(河北)生物科技有限公司 2024-10-11 CN claimed
US-5209724-A Buffering local anesthetic, reducing pain and irritation on injection M.D., INC. 1993-05-11 US claimed
US-5149320-A Using parenteral solution containing sodium bicarbonate and dissolved carbon dioxide M.D., INC. 1992-09-22 US claimed
US-5008101-A Increasing absorbance of ultraviolet light DOW CORNING CORPORATION (US) 1991-04-16 US claimed
EP-0292554-A4 MOISTURE-RESISTANT SKIN TREATMENT COMPOSITIONS. RITZ GROUP LTD CHARLES (US) 1989-02-22 EP claimed
EP-0292554-A1 MOISTURE-RESISTANT SKIN TREATMENT COMPOSITIONS CHARLES OF THE RITZ GROUP LTD. (US) 1988-11-30 EP claimed
US-4781914-A POLYGLYCERYL-8 OLEATE, WATERPROOFING CHARLES OF THE RITZ GROUP LTD. (US) 1988-11-01 US claimed
WO-1988004167-A1 MOISTURE-RESISTANT SKIN TREATMENT COMPOSITIONS CHARLES OF THE RITZ GROUP LTD. (US) 1988-06-16 WO claimed
US-4749563-A SECONDARY AMIDE OF SATURATED OR UNSATURATED FATTY ACID CHARLES OF THE RITZ GROUP LTD. (US) 1988-06-07 US claimed
US-4603046-A TRI(HYDROXYALKYL)RUTOSIDE, HUMECTANTS CHARLES OF THE RITZ GROUP LTD. (US) 1986-07-29 US claimed
US-4597963-A Moisture-resistant skin treatment compositions CHARLES OF THE RITZ GROUP LTD. (US) 1986-07-01 US claimed