SCHEMBL369461

SCHEMBL369461

CC(COC(=O)c1ccc(N)cc1)OC(=O)c1ccc(N)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 4/20 0.60
ADRB1 P08588 4/20 0.60
ADRB3 P13945 4/20 0.60
LMNA P02545 3/20 0.59
CYP1A2 P05177 3/20 0.59
CYP3A4 P08684 3/20 0.59
MAOA P21397 2/20 0.59
SCN1A P35498 2/20 0.54
SCN2A Q99250 2/20 0.54
SCN3A Q9NY46 2/20 0.54
TSHR P16473 2/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
PDE4D Q08499 1/20 0.53
PHLPP2 Q6ZVD8 1/20 0.51
MAPT P10636 2/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP2D6 P10635 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL1049002 0.95 ADRB2 (0.56) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL5015380 0.94 ADRB2 (0.55) ADRB2ADRB1ADRB3LMNACYP1A2
Hydrochloric Acid SCHEMBL9420534 0.93 ADRB2 (0.53) ADRB2ADRB1ADRB3LMNACYP1A2
Isobutamben SCHEMBL25178 0.88 ADRB2 (0.65) ADRB2ADRB1ADRB3LMNACYP1A2
Isobutamben SCHEMBL4756252 0.86 ADRB2 (0.63) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL24055108 0.85 MAPT (0.49) ADRB2ADRB1ADRB3LMNATSHR
SCHEMBL12559135 0.85 ALDH1A1 (0.61) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL1784739 0.85 ADRB2 (0.59) ADRB2ADRB1ADRB3TSHRMAPT
SCHEMBL16217637 0.85 ALDH1A1 (0.61) ADRB2ADRB1ADRB3LMNACYP1A2
SCHEMBL1580003 0.85 CA12 (0.62) ADRB2ADRB1ADRB3LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118931250-A Modified graphene oxide and polyurea anticorrosive coating composition and method for preparing polyurea anticorrosive coating 中国石油化工股份有限公司 2024-11-12 CN claimed
CN-117757250-A High-temperature-resistant infiltration-resistant thermal transfer TPU alloy material and preparation and application thereof 美瑞新材料股份有限公司 2024-03-26 CN claimed
CN-117736573-A Preparation method of low-noise high-wear-resistance polymer elastomer composite material 长春工业大学 2024-03-22 CN claimed
US-8524852-B2 Thermoset polyurethanes based on moisture-resistance polyols for use in golf balls ACUSHNET COMPANY (US) 2013-09-03 US claimed
US-8288478-B2 Golf balls based on thermoplastic polyurethanes comprising moisture-resistant polyols ACUSHNET COMPANY (US) 2012-10-16 US claimed
US-20110256961-A1 THERMOSET POLYURETHANES BASED ON MOISTURE-RESISTANCE POLYOLS FOR USE IN GOLF BALLS JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2011-10-20 US claimed
US-20110207556-A1 GOLF BALLS BASED ON THERMOPLASTIC POLYURETHANES COMPRISING MOISTURE-RESISTANT POLYOLS JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2011-08-25 US claimed
US-7115703-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2006-10-03 US claimed
US-6903178-B2 Acid-functional polyurethane and polyurea compositions for golf balls ACUSHNET COMPANY (US) 2005-06-07 US claimed
US-20040220376-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US claimed
US-20040014535-A1 Acid-functional polyurethane and polyurea compositions for golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-01-22 US claimed
US-6610812-B1 Acid functional group based on a carboxylic, sulfonic or phosphonic acid ACUSHNET COMPANY 2003-08-26 US claimed
US-20030153716-A1 GOLF BALL COMPOSITIONS COMPRISING A NOVEL ACID FUNCTIONAL POLYURETHANE, POLYUREA, OR COPOLYMER THEREOF JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-08-14 US claimed
US-6403063-B1 APPLYING POLYUREA; CURING SAWYER KENNETH I (US) 2002-06-11 US claimed
US-6401724-B1 POLYUREA-FORMING COMPOSITION SUCH AS 1)AN AMINOBENZOIC ACID ESTER OR AMIDE OF A POSSIBLY OLIGOMERIC POLYOL OR POLYAMINE OR AN AROMATIC DIAMINE AND 2)A POLYISOCYANATE PAR PHARMACEUTICALS INCORPORATED 2002-06-11 US claimed
EP-0630666-B1 Polyurea covered golf ball ACUSHNET CO (US) 1998-11-11 EP claimed
US-5484870-A CLICK, FEEL; SHEAR AND CUT RESISTANCE; DURABILITY ACUSHNET COMPANY (US) 1996-01-16 US claimed
EP-0630666-A2 Polyurea covered golf ball ACUSHNET COMPANY (US) 1994-12-28 EP claimed
US-12516180-B2 Rubber composition based on epoxy resin and an aminobenzoate derivative COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2026-01-06 US disclosed
US-3932360-A Polyurethane elastomers prepared from diamine curing agents POLAROID CORPORATION (US) 1976-01-13 US disclosed