Alpha-Tocopherol

Alpha-Tocopherol

SCHEMBL25189686

COC.Cc1c(C)c2c(c(C)c1O)CC[C@@](C)(CCCC(C)CCCC(C)CCCC(C)C)O2

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.93
TTPA P49638 3/20 0.93
MAPT P10636 2/20 0.93
MEN1 O00255 2/20 0.93
KMT2A Q03164 2/20 0.93
GSTP1 P09211 1/20 0.93
USP2 O75604 1/20 0.93
THRB P10828 1/20 0.93
CYP2C9 P11712 1/20 0.93
CYP2C19 P33261 1/20 0.93
NR1I2 O75469 2/20 0.80
ALOX5 P09917 1/20 0.74
PDE4A P27815 1/20 0.69
PDE3A Q14432 1/20 0.69
GSTO1 P78417 2/20 0.68
PSEN1 P49768 2/20 0.67
PTPN1 P18031 1/20 0.63
AKT1 P31749 4/20 0.55
PDPK1 O15530 1/20 0.55
PHLPP1 O60346 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alpha-Tocopherol SCHEMBL2363382 1.00 LMNA (0.93) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL14167439 0.97 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL14297170 0.97 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tochopherol SCHEMBL22303 0.97 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL3059188 0.97 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL16451007 0.97 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tochopherol SCHEMBL14315133 0.97 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL17874901 0.97 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
Alpha-Tocopherol SCHEMBL20817063 0.97 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A
SCHEMBL8084077 0.97 LMNA (1.00) LMNATTPAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260021113-A1 INTRAVITREAL CORTICOSTEROID EXTENDED RELEASE IMPLANT AND METHODS OF USE EYEDEA BIO LLC (US) 2026-01-22 US disclosed
US-12433900-B2 Intravitreal corticosteroid extended release implant and methods of use EYEDEA BIO, LLC (US) 2025-10-07 US disclosed
US-20240415850-A1 INTRAVITREAL CORTICOSTEROID EXTENDED RELEASE IMPLANT AND METHODS OF USE EYEDEA BIO, LLC 2024-12-19 US disclosed
EP-4433092-A1 INTRAVITREAL CORTICOSTEROID EXTENDED RELEASE IMPLANT AND METHODS OF USE Eyedea Bio, Llc (US) 2024-09-25 EP disclosed
WO-2023092087-A1 INTRAVITREAL CORTICOSTEROID EXTENDED RELEASE IMPLANT AND METHODS OF USE EYEDEA BIO, LLC (US) 2023-05-25 WO disclosed
CN-101087774-B Asymmetric hydrogenation of alkenes using chiral iridium complexes DSM IP ASSETS B.V. (NL) 2012-02-08 CN disclosed
CN-101087774-A Asymmetric hydrogenation of alkenes using chiral iridium complexes DSM IP ASSETS BV (NL) 2007-12-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021113-A1 INTRAVITREAL CORTICOSTEROID EXTENDED RELEASE IMPLANT AND METHODS OF USE NR3C2, NR3C1, STARD3 LMNA 2539/4885TTPA 337/4885MAPT 219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.