SCHEMBL25190841

SCHEMBL25190841

CCN(CC)S(=O)(=O)c1ccc(C(=O)C=Cc2ccc(O)c(Cl)c2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 7/20 0.69
PTGS2 P35354 1/20 0.58
LMNA P02545 2/20 0.55
CXCL12 P48061 2/20 0.50
MAPT P10636 3/20 0.49
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 2/20 0.49
HPGD P15428 2/20 0.49
MAOB P27338 1/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
JAK2 O60674 1/20 0.48
USP2 O75604 1/20 0.48
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
THRB P10828 1/20 0.48
ALOX12 P18054 1/20 0.48
MAPK1 P28482 1/20 0.48
HTT P42858 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25216157 1.00 P4HB (0.69) P4HBPTGS2LMNACXCL12MAPT
SCHEMBL30383872 1.00 P4HB (0.69) P4HBPTGS2LMNACXCL12MAPT
SCHEMBL31233141 1.00 P4HB (0.69) P4HBPTGS2LMNACXCL12MAPT
SCHEMBL30383278 0.88 PTGS2 (0.63) P4HBPTGS2LMNACXCL12MAPT
SCHEMBL25212492 0.88 PTGS2 (0.63) P4HBPTGS2LMNACXCL12MAPT
SCHEMBL30384088 0.88 PTGS2 (0.63) P4HBPTGS2LMNACXCL12MAPT
SCHEMBL25196912 0.88 PTGS2 (0.63) P4HBPTGS2LMNACXCL12MAPT
SCHEMBL25203658 0.86 P4HB (0.69) P4HBLMNACXCL12MAPTALDH1A1
SCHEMBL25202011 0.81 P4HB (0.67) P4HBLMNAMAPTALDH1A1MAOB
SCHEMBL25221629 0.81 P4HB (0.67) P4HBLMNAMAPTALDH1A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B P4HB 552/4885PTGS2 704/4885LMNA 1180/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 P4HB 469/4885PTGS2 330/4885LMNA 1817/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 P4HB 469/4885PTGS2 330/4885LMNA 1817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.