SCHEMBL25202011

SCHEMBL25202011

CCN(CC)S(=O)(=O)c1ccc(C(=O)C=Cc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 5/20 0.67
LMNA P02545 3/20 0.62
SMN1; SMN2 Q16637 3/20 0.56
CA12 O43570 1/20 0.56
CA2 P00918 1/20 0.56
RAB9A P51151 1/20 0.56
CA9 Q16790 1/20 0.56
SLC22A6 Q4U2R8 1/20 0.56
SLC22A8 Q8TCC7 1/20 0.56
ABCC2 Q92887 1/20 0.56
SLC22A12 Q96S37 1/20 0.56
UGT1A7 Q9HAW7 1/20 0.56
SLC22A11 Q9NSA0 1/20 0.56
POLB P06746 1/20 0.55
XDH P47989 1/20 0.53
MAOB P27338 1/20 0.52
MAPT P10636 3/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
TAS2R14 Q9NYV8 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25221629 1.00 P4HB (0.67) P4HBLMNASMN1; SMN2CA12CA2
SCHEMBL25244774 0.85 LMNA (0.74) P4HBLMNASMN1; SMN2RAB9AXDH
SCHEMBL25190857 0.85 LMNA (0.74) P4HBLMNASMN1; SMN2RAB9AXDH
SCHEMBL25193155 0.85 LMNA (0.74) P4HBLMNASMN1; SMN2RAB9AXDH
SCHEMBL25189337 0.85 P4HB (0.61) P4HBLMNARAB9APOLBMAOB
Etebenecid SCHEMBL1643610 0.84 SMN1; SMN2 (0.75) LMNASMN1; SMN2CA12CA2RAB9A
SCHEMBL25190841 0.81 P4HB (0.69) P4HBLMNAPOLBMAOBMAPT
SCHEMBL25216157 0.81 P4HB (0.69) P4HBLMNAPOLBMAOBMAPT
SCHEMBL25203658 0.81 P4HB (0.69) P4HBLMNAPOLBMAPTMEN1
SCHEMBL31233141 0.81 P4HB (0.69) P4HBLMNAPOLBMAOBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B P4HB 552/4885LMNA 1180/4885SMN1; SMN2 3415/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 P4HB 469/4885LMNA 1817/4885SMN1; SMN2 4161/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 P4HB 469/4885LMNA 1817/4885SMN1; SMN2 4161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.