SCHEMBL25233397

SCHEMBL25233397

COC(=O)c1ccc(/C=C/C(=O)c2ccc(OCCCC(=O)O)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.66
▸ NPC1 O15118 2/20 0.66
▸ LMNA P02545 1/20 0.66
▸ ABCG2 Q9UNQ0 2/20 0.60
▸ BCHE P06276 6/20 0.57
▸ ACHE P22303 6/20 0.57
▸ MAOB P27338 4/20 0.56
▸ PPARA Q07869 1/20 0.56
▸ PTPN1 P18031 1/20 0.55
▸ F3 P13726 1/20 0.55
▸ MAOA P21397 1/20 0.54
▸ RAB9A P51151 1/20 0.54
▸ KMT2A Q03164 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25230131 0.90 MAOB (0.70) MAPTNPC1LMNAABCG2BCHE
SCHEMBL25219612 0.88 MAOB (0.70) MAPTNPC1ABCG2BCHEACHE
SCHEMBL25193666 0.88 MAOB (0.71) MAPTNPC1LMNAABCG2MAOB
SCHEMBL11461543 0.87 ABCG2 (0.62) MAPTNPC1ABCG2BCHEACHE
SCHEMBL25198610 0.87 ABCG2 (0.62) MAPTNPC1ABCG2BCHEACHE
SCHEMBL7340260 0.86 ABCG2 (0.73) MAPTNPC1LMNAABCG2BCHE
SCHEMBL7340257 0.86 ABCG2 (0.73) MAPTNPC1LMNAABCG2BCHE
SCHEMBL25214787 0.86 NPC1 (0.71) MAPTNPC1LMNAABCG2MAOB
SCHEMBL25193715 0.86 BCHE (0.70) BCHEACHEMAOBPPARAMAOA
SCHEMBL25199681 0.85 MAOB (0.68) ABCG2BCHEACHEMAOBPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885NPC1 1378/4885LMNA 1180/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885NPC1 1908/4885LMNA 1817/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885NPC1 1908/4885LMNA 1817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback