Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30991587 | 0.82 | CYP3A4 (0.57) | CYP3A4MAPK1ABCB1MAPTKDM4E | |
| SCHEMBL25199321 | 0.82 | GABRA1 (0.58) | CYP3A4MAPK1ABCB1MAPTKDM4E | |
| SCHEMBL25194801 | 0.82 | CYP3A4 (0.57) | CYP3A4MAPK1ABCB1MAPTKDM4E | |
| SCHEMBL25183297 | 0.81 | KDM4E (0.46) | CYP3A4MAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL25187247 | 0.77 | CYP3A4 (0.43) | CYP3A4MAPK1ABCB1MAPTTHRB | |
| SCHEMBL25192829 | 0.77 | CYP3A4 (0.59) | CYP3A4MAPK1DPP4ABCB1MAPT | |
| SCHEMBL25192661 | 0.77 | CYP3A4 (0.51) | CYP3A4MAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL25190038 | 0.77 | MAOB (0.47) | CYP3A4MAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL25203257 | 0.76 | MAPT (0.42) | CYP3A4MAPK1MAPTTHRBKDM4E | |
| SCHEMBL1659934 | 0.75 | CYP3A4 (0.48) | CYP3A4MAPK1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11952358-B2 | Flavan-3-ol analogs and anti-inflammatory activity | HONG KONG BAPTIST UNIVERSITY (CN) | 2024-04-09 | — | — | US | disclosed |
| US-20230159482-A1 | FLAVAN-3-OL ANALOGS AND ANTI-INFLAMMATORY ACTIVITY | HONG KONG BAPTIST UNIVERSITY (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230159482-A1 | FLAVAN-3-OL ANALOGS AND ANTI-INFLAMMATORY ACTIVITY | HONG KONG BAPTIST UNIVERSITY (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230159482-A1 | FLAVAN-3-OL ANALOGS AND ANTI-INFLAMMATORY ACTIVITY | HONG KONG BAPTIST UNIVERSITY (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11952358-B2 | Flavan-3-ol analogs and anti-inflammatory activity | IL1A, IL6, IL1B | CYP3A4 965/4885MAPK1 222/4885DPP4 1871/4885 |
| US-20230159482-A1 | FLAVAN-3-OL ANALOGS AND ANTI-INFLAMMATORY ACTIVITY | IL1A, IL6, IL1B | CYP3A4 965/4885MAPK1 222/4885DPP4 1871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.