Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833806 | 0.80 | MAPK1 (0.44) | MAPK1CYP2C19FAAHP2RX7HSD17B10 | |
| SCHEMBL1740252 | 0.77 | MAPK1 (0.60) | MAPK1CYP2C19FAAHP2RX7EPHX1 | |
| Benzoic Acid SCHEMBL1739284 | 0.74 | MAPK1 (0.56) | MAPK1CYP2C19FAAHP2RX7EPHX1 | |
| SCHEMBL7417055 | 0.68 | MAPK1 (1.00) | MAPK1CYP2C19FAAHP2RX7EPHX1 | |
| SCHEMBL23833796 | 0.68 | MAPK1 (0.48) | MAPK1CYP2C19FAAHP2RX7EPHX1 | |
| SCHEMBL25265200 | 0.67 | ALDH1A1 (0.35) | HSD17B10ALDH1A1KDM4EMEN1HTT | |
| SCHEMBL25199371 | 0.66 | HSD17B10 (0.42) | MAPK1CYP2C19FAAHHSD17B10CTSL | |
| SCHEMBL8022535 | 0.63 | CYP2C19 (0.52) | MAPK1CYP2C19FAAHALDH1A1MAPT | |
| SCHEMBL8018575 | 0.63 | MAPK1 (0.52) | MAPK1CYP2C19FAAHGRM2GRM3 | |
| SCHEMBL1421026 | 0.63 | FAAH (1.00) | FAAHEPHX1HSD17B10CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158178-A1 | Radionuclide Tracers of 1-Amino-3,4-Difluorocyclopentane-1-Carboxylic Acid, Derivatives, and Uses Thereof | UNIV EMORY (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158178-A1 | Radionuclide Tracers of 1-Amino-3,4-Difluorocyclopentane-1-Carboxylic Acid, Derivatives, and Uses Thereof | AFF1, METTL3, VHL | MAPK1 3027/4885CYP2C19 2519/4885FAAH 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.