SCHEMBL482965

SCHEMBL482965

Cc1ccc(/C=C/C(=O)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.77
TLR9 Q9NR96 2/20 0.77
CRHBP P24387 1/20 0.77
CRHR2 Q13324 1/20 0.77
CYP1B1 Q16678 3/20 0.74
KMT2A Q03164 3/20 0.74
RAB9A P51151 2/20 0.74
NPC1 O15118 1/20 0.74
CASP3 P42574 1/20 0.74
SMN1; SMN2 Q16637 1/20 0.74
SENP8 Q96LD8 1/20 0.74
SENP7 Q9BQF6 1/20 0.74
SENP6 Q9GZR1 1/20 0.74
MAOB P27338 6/20 0.71
MAOA P21397 4/20 0.69
POLB P06746 2/20 0.69
ALDH1A1 P00352 2/20 0.66
CYP3A4 P08684 1/20 0.66
HPGD P15428 1/20 0.66
HSD17B3 P37058 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482966 1.00 MAPT (0.77) MAPTTLR9CRHBPCRHR2CYP1B1
SCHEMBL5950050 1.00 MAPT (0.77) MAPTTLR9CRHBPCRHR2CYP1B1
SCHEMBL5950048 1.00 MAPT (0.77) MAPTTLR9CRHBPCRHR2CYP1B1
SCHEMBL2911444 0.93 TLR9 (0.87) MAPTTLR9CRHBPCRHR2CYP1B1
SCHEMBL2911445 0.93 TLR9 (0.87) MAPTTLR9CRHBPCRHR2CYP1B1
4,4'-Dimethylchalcone SCHEMBL979560 0.88 MAPT (1.00) MAPTCYP1B1KMT2ARAB9ASMN1; SMN2
4,4'-Dimethylchalcone SCHEMBL979559 0.88 MAPT (1.00) MAPTCYP1B1KMT2ARAB9ASMN1; SMN2
SCHEMBL25185026 0.87 CRHBP (1.00) MAPTTLR9CRHBPCRHR2CYP1B1
SCHEMBL25205299 0.87 MAPT (0.79) MAPTTLR9CRHBPCRHR2CYP1B1
SCHEMBL25200425 0.87 CRHBP (1.00) MAPTTLR9CRHBPCRHR2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0368327-B1 Light-sensitive composition FUJI PHOTO FILM CO LTD (JP) 1995-02-15 EP claimed
US-5202221-A Photocrosslinkable copolymer having maleimido side chain, cyanine dye sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-04-13 US claimed
US-5110709-A Photoresists of excellent image resolution FUJI PHOTO FILM CO., LTD. (JP) 1992-05-05 US claimed
US-5002853-A Polymeric Sulfonyloxy-Amides and Iides FUJI PHOTO FILM CO., LTD. (JP) 1991-03-26 US claimed
US-4148658-A BENZOYLMETHYLENE-BENSOTHIAZOLYIDEND-THIAZOLIDONE COMPOUND, AMINE, AND AMINOARYLCARBONYL COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1979-04-10 US claimed
EP-2618215-B1 Method for producing a lithographic printing plate FUJIFILM CORP (JP) 2017-07-05 EP disclosed
EP-1621337-B1 Image recording material and lithographic printing plate precursor FUJIFILM CORP (JP) 2017-03-22 EP disclosed
EP-1916568-B1 Use of a developing solution for lithographic printing plates and production method of lithographic printing plate FUJIFILM CORP (JP) 2017-02-08 EP disclosed
EP-1696268-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2016-11-09 EP disclosed
EP-3086176-A1 A LITHOGRAPHIC PRINTING METHOD Fujifilm Corporation (JP) 2016-10-26 EP disclosed
EP-3086177-A1 METHOD FOR PREPARING A LITHOGRAPHIC PRINTING PLACE PRECURSOR Fujifilm Corporation (JP) 2016-10-26 EP disclosed
EP-2085821-B1 Dye-containing negative curable composition, color filter and method of producing color filter FUJIFILM CORP (JP) 2016-06-01 EP disclosed
EP-0368327-A2 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1990-05-16 EP disclosed
EP-0320264-A2 Colour filter MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1989-06-14 EP disclosed
EP-0301520-A2 Dry presensitized plate Fuji Photo Film Co., Ltd. (JP) 1989-02-01 EP disclosed
US-4772534-A PHOTORESISTS FUJI PHOTO FILM CO., LTD. (JP) 1988-09-20 US disclosed
US-4701399-A Photosensitive composition with 2-halomethyl-5-substituted-1,3,4-oxadiazole FUJI PHOTO FILM CO., LTD. (JP) 1987-10-20 US disclosed
US-4555474-A IMPROVED PHOTOSENSITIVITY USING HETEROCYCLIC KETONE PHOTOINITIATORS; LITHOGRAPHY; PHOTORESISTS FUJI PHOTO FILM CO., LTD. (JP) 1985-11-26 US disclosed
US-4504573-A QUINAZOLINONE INITIATORS FUJI PHOTO FILM CO., LTD. (JP) 1985-03-12 US disclosed
US-4148658-A BENZOYLMETHYLENE-BENSOTHIAZOLYIDEND-THIAZOLIDONE COMPOUND, AMINE, AND AMINOARYLCARBONYL COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1979-04-10 US disclosed