Thiobenzoic Acid

Thiobenzoic Acid

SCHEMBL2520397

CC(Cc1ccccc1)OC(=S)c1ccc(Br)cc1.OC(=S)c1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
MGLL Q99685 1/20 0.40
HSP90AA1 P07900 1/20 0.39
ALDH1A1 P00352 4/20 0.39
HPGD P15428 2/20 0.39
DUSP3 P51452 1/20 0.39
PTPN5 P54829 1/20 0.39
PTPN11 Q06124 1/20 0.39
SIGMAR1 Q99720 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GAA P10253 1/20 0.36
PPARG P37231 2/20 0.35
PPARD Q03181 2/20 0.35
PPARA Q07869 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL2770810 0.91 NPC1 (0.41) NPC1RAB9AALDH1A1SIGMAR1TRPA1
Thiobenzoic Acid SCHEMBL28693475 0.86 PPARG (0.40) NPC1RAB9AALDH1A1MAPTGAA
Thiobenzoic Acid SCHEMBL12971268 0.85 KMT2A (0.33) KMT2AMEN1NPC1RAB9AMGLL
Thiobenzoic Acid SCHEMBL29012058 0.73 ALDH1A1 (0.43) KMT2AMEN1NPC1RAB9AHSP90AA1
Thiobenzoic Acid SCHEMBL13724295 0.72 ALDH1A1 (0.34) NPC1RAB9AALDH1A1HPGDMAPT
SCHEMBL2520394 0.71 KMT2A (0.44) KMT2AMEN1NPC1RAB9AMGLL
Thiobenzoic Acid SCHEMBL17975524 0.70 KMT2A (0.36) KMT2AMEN1NPC1RAB9AMGLL
Thiobenzoic Acid SCHEMBL144057 0.69 HCAR2 (0.44) KMT2AMEN1HSP90AA1ALDH1A1HPGD
Thiobenzoic Acid SCHEMBL28761914 0.69 LMNA (0.34) KMT2AMEN1NPC1RAB9AALDH1A1
SCHEMBL1742490 0.69 CES2 (0.50) MGLLALDH1A1HPGDDUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080071003-A1 Method for Producing Molecularly Imprinted Polymers UNIVERSITY OF DORTMUND INFU (DE) 2008-03-20 US claimed
EP-1383828-A4 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION BIO LAYER PTY LTD (AU) 2006-10-04 EP claimed
US-6858309-B2 Methods of polymerization POLYMERAT PTY. LTD. (AU) 2005-02-22 US claimed
EP-1383828-A1 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION Polymerat Pty Ltd (AU) 2004-01-28 EP claimed
US-20030088028-A1 Methods of polymerization ANTEO TECHNOLOGIES PTY LTD (AU) 2003-05-08 US claimed
WO-2002079305-A1 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION POLYMERAT PTY LTD (AU) 2002-10-10 WO claimed
WO-2023099310-A1 PREPARATION OF HIGH SOLID CONTENT, SURFACTANT-FREE LATEX USING FUNCTIONAL AMPHIPHILIC WATERBORNE MACRO-RAFT AGENT BASF SE (DE) 2023-06-08 WO disclosed
US-9309329-B2 Method for preparing pH-insensitive surfactant free polymer particle dispersion in aqueous medium ARKEMA INC. (US) 2016-04-12 US disclosed
US-20110251329-A1 METHOD FOR PREPARING pH-INSENSITIVE SURFACTANT FREE POLYMER PARTICLE DISPERSION IN AQUEOUS MEDIUM ARKEMA INC. (US) 2011-10-13 US disclosed
US-20080071003-A1 Method for Producing Molecularly Imprinted Polymers UNIVERSITY OF DORTMUND INFU (DE) 2008-03-20 US disclosed
US-6858309-B2 Methods of polymerization POLYMERAT PTY. LTD. (AU) 2005-02-22 US disclosed
US-20030088028-A1 Methods of polymerization ANTEO TECHNOLOGIES PTY LTD (AU) 2003-05-08 US disclosed