Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292201 | 0.89 | MAPT (0.45) | NISCHMAPTRPS6KB2KDM4EALDH1A1 | |
| SCHEMBL2572924 | 0.71 | NOS3 (0.41) | NISCHMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL131539 | 0.71 | NOS3 (0.55) | NOS3NOS1NOS2 | |
| SCHEMBL1645947 | 0.70 | NOS3 (0.44) | ALDH1A1HPGDNOS3NOS1NOS2 | |
| SCHEMBL2570914 | 0.69 | NOS3 (0.40) | SMN1; SMN2NOS3NOS1NOS2 | |
| SCHEMBL9319771 | 0.69 | CHRNB4 (0.44) | NISCHMAPTALDH1A1HPGDNPC1 | |
| SCHEMBL1607048 | 0.69 | RPS6KB2 (0.42) | NISCHMAPTRPS6KB2KDM4EALDH1A1 | |
| SCHEMBL1646929 | 0.68 | NOS3 (0.39) | NISCHNPC1NOS3NOS1NOS2 | |
| SCHEMBL15664526 | 0.68 | NISCH (0.46) | NISCHMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL27238090 | 0.68 | RPS6KB2 (0.41) | NISCHMAPTRPS6KB2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4556468-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University of KwaZulu-Natal (ZA) | 2025-05-21 | — | — | EP | claimed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | claimed |
| EP-4185571-B1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIV OF KWAZULU NATAL (ZA) | 2026-05-20 | — | — | EP | disclosed |
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2025-10-14 | — | — | US | disclosed |
| EP-4556468-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University of KwaZulu-Natal (ZA) | 2025-05-21 | — | — | EP | disclosed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | disclosed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | disclosed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | disclosed |
| EP-4185571-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University Of Kwazulu-Natal (ZA) | 2023-05-31 | — | — | EP | disclosed |
| CN-116057047-A | Synthesis of heterocyclic compounds from carboxamides and carboxamide derivatives and haloalkanols | 夸祖鲁-纳塔尔大学 | 2023-05-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | NAAA, CNR2, AADAC | NISCH 46/4885MAPT 4373/4885RPS6KB2 3063/4885 |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | NAAA, CNR2, AADAC | NISCH 46/4885MAPT 4373/4885RPS6KB2 3063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.