Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.41 |
| ▸ | RELA | Q04206 | 3/20 | 0.41 |
| ▸ | FOS | P01100 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25204309 | 0.89 | NISCH (0.46) | MAPTNISCHRPS6KB2NFKB1NFKB2 | |
| SCHEMBL1028921 | 0.70 | GPR35 (0.34) | ALDH1A1GAA | |
| SCHEMBL21925885 | 0.69 | HDAC8 (0.31) | — | |
| SCHEMBL29839941 | 0.69 | MAPT (0.45) | MAPTNISCHRPS6KB2KDM4EALDH1A1 | |
| SCHEMBL218213 | 0.69 | SMN1; SMN2 (0.50) | SMN1; SMN2 | |
| SCHEMBL15873586 | 0.69 | RPS6KB2 (0.50) | MAPTNISCHRPS6KB2KDM4EALDH1A1 | |
| SCHEMBL29420719 | 0.69 | SMN1; SMN2 (0.50) | SMN1; SMN2 | |
| Fluoride SCHEMBL491501 | 0.68 | L3MBTL1 (0.55) | MAPTRPS6KB2NFKB1NFKB2RELA | |
| SCHEMBL351341 | 0.68 | ADRA2A (0.39) | NISCHSMN1; SMN2CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL9791151 | 0.68 | SMN1; SMN2 (0.40) | NISCHNFKB1NFKB2RELAFOS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185571-B1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIV OF KWAZULU NATAL (ZA) | 2026-05-20 | — | — | EP | claimed |
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2025-10-14 | — | — | US | claimed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | claimed |
| EP-4185571-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University Of Kwazulu-Natal (ZA) | 2023-05-31 | — | — | EP | claimed |
| CN-115108987-B | N-substituted indenoisoquinolinone derivative and preparation method thereof | 华侨大学 | 2023-05-26 | — | — | CN | claimed |
| CN-115108987-A | N-substituted indenoisoquinolinone derivative and preparation method thereof | 华侨大学 | 2022-09-27 | — | — | CN | claimed |
| CN-112680153-A | Low-temperature conductive slurry | 江苏碳导材料科技有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-106986841-A | A kind of synthetic method of the dihydro-oxazole of 2 thiophenyl 4,5 | 常州大学 | 2017-07-28 | — | — | CN | claimed |
| CN-1138855-A | Phenylthio-oxazoline derivatives | BAYER AG (DE) | 1996-12-25 | — | — | CN | claimed |
| JP-57035589-A | — | — | None | — | — | JP | disclosed |
| EP-4185571-B1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIV OF KWAZULU NATAL (ZA) | 2026-05-20 | — | — | EP | disclosed |
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2025-10-14 | — | — | US | disclosed |
| EP-4556468-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University of KwaZulu-Natal (ZA) | 2025-05-21 | — | — | EP | disclosed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | disclosed |
| CN-115108987-B | N-substituted indenoisoquinolinone derivative and preparation method thereof | 华侨大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-115108987-A | N-substituted indenoisoquinolinone derivative and preparation method thereof | 华侨大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-107721874-B | Method for preparing nitrate compounds by adopting micro-flow field reaction technology | 南京工业大学 | 2020-05-19 | — | — | CN | disclosed |
| CN-106986841-A | A kind of synthetic method of the dihydro-oxazole of 2 thiophenyl 4,5 | 常州大学 | 2017-07-28 | — | — | CN | disclosed |
| CN-1138855-A | Phenylthio-oxazoline derivatives | BAYER AG (DE) | 1996-12-25 | — | — | CN | disclosed |
| JP-S5735589-A | 5-THIENYLOXAZOLINE DERIVATIVE, ITS PREPARATION AND SELECTIVE HERBICIDE | NIPPON SODA CO LTD | 1982-02-26 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | NAAA, CNR2, AADAC | MAPT 4373/4885NISCH 46/4885RPS6KB2 3063/4885 |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | NAAA, CNR2, AADAC | MAPT 4373/4885NISCH 46/4885RPS6KB2 3063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.