Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 4/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | HCK | P08631 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30349392 | 1.00 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1LMNASMN1; SMN2SRC | |
| SCHEMBL30542285 | 0.89 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1LMNASMN1; SMN2PIK3CA | |
| SCHEMBL30399768 | 0.88 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNASMN1; SMN2PIK3CA | |
| SCHEMBL26176365 | 0.88 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNASMN1; SMN2PIK3CA | |
| SCHEMBL30349319 | 0.83 | EGFR (0.42) | L3MBTL1ALDH1A1LMNASMN1; SMN2SRC | |
| SCHEMBL25211151 | 0.83 | EGFR (0.42) | L3MBTL1ALDH1A1LMNASMN1; SMN2SRC | |
| SCHEMBL20292779 | 0.82 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1LMNASMN1; SMN2PTPN11 | |
| SCHEMBL20210703 | 0.82 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1LMNASMN1; SMN2SRC | |
| SCHEMBL7060611 | 0.82 | SRC (0.49) | L3MBTL1ALDH1A1LMNASMN1; SMN2SRC | |
| SCHEMBL30400147 | 0.79 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1LMNASMN1; SMN2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | disclosed |
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | L3MBTL1 2548/4885ALDH1A1 3447/4885LMNA 3407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.