Sugi Predict

Sugi Predict / Compounds / SCHEMBL25211151

SCHEMBL25211151

SCHEMBL25211151

Cc1ccc(S(=O)(=O)n2cc(-c3ccc4ncccc4c3)c3c(-c4cnn(C)c4)ncnc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 2/20 0.42
▸ ERBB2 P04626 1/20 0.42
▸ ERBB4 Q15303 1/20 0.42
▸ MET P08581 13/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ KIT P10721 1/20 0.40
▸ ABL1 P00519 2/20 0.40
▸ PIK3CD O00329 1/20 0.40
▸ HCK P08631 1/20 0.40
▸ SRC P12931 1/20 0.40
▸ KDR P35968 1/20 0.40
▸ PIK3CA P42336 1/20 0.40
▸ PIK3CB P42338 1/20 0.40
▸ MTOR P42345 1/20 0.40
▸ PIK3CG P48736 1/20 0.40
▸ EPHB4 P54760 1/20 0.40
▸ PRKDC P78527 1/20 0.40
▸ DYRK1A Q13627 2/20 0.40
▸ WNT1 P04628 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30349319 1.00 EGFR (0.42) EGFRERBB2ERBB4METL3MBTL1
SCHEMBL30400147 0.88 L3MBTL1 (0.44) EGFRERBB2ERBB4METL3MBTL1
SCHEMBL26176364 0.88 L3MBTL1 (0.44) EGFRERBB2ERBB4METL3MBTL1
SCHEMBL30349392 0.83 L3MBTL1 (0.45) EGFRL3MBTL1ABL1PIK3CDHCK
SCHEMBL25209802 0.83 L3MBTL1 (0.45) EGFRL3MBTL1ABL1PIK3CDHCK
SCHEMBL30399768 0.79 L3MBTL1 (0.48) L3MBTL1PIK3CAALDH1A1LMNASMN1; SMN2
SCHEMBL26176365 0.79 L3MBTL1 (0.48) L3MBTL1PIK3CAALDH1A1LMNASMN1; SMN2
SCHEMBL20292779 0.77 L3MBTL1 (0.53) L3MBTL1ALDH1A1LMNASMN1; SMN2PTPN11
SCHEMBL30542285 0.76 L3MBTL1 (0.45) L3MBTL1PIK3CAALDH1A1LMNASMN1; SMN2
SCHEMBL25201354 0.73 EGFR (0.50) EGFRERBB2ERBB4METABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129104-A1 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF TENARX, INC. 2025-04-24 — — US disclosed
US-20230167133-A1 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF VICKERS VENTURE FUND VI PTE. LTD. (SG) 2023-06-01 — — US disclosed
US-20230167133-A1 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF VICKERS VENTURE FUND VI PTE. LTD. (SG) 2023-06-01 — — US disclosed
US-20230167133-A1 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF VICKERS VENTURE FUND VI PTE. LTD. (SG) 2023-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167133-A1 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF DYRK1A, DYRK1B, DYRK2 EGFR 2943/4885ERBB2 647/4885ERBB4 1596/4885
US-20250129104-A1 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF DYRK1A, DYRK1B, DYRK2 EGFR 2943/4885ERBB2 647/4885ERBB4 1596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.