Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 15/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.38 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26176364 | 1.00 | L3MBTL1 (0.44) | L3MBTL1METDYRK1AWNT1ALDH1A1 | |
| SCHEMBL25211151 | 0.88 | EGFR (0.42) | L3MBTL1METDYRK1AWNT1ALDH1A1 | |
| SCHEMBL30349319 | 0.88 | EGFR (0.42) | L3MBTL1METDYRK1AWNT1ALDH1A1 | |
| SCHEMBL26176365 | 0.84 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNASMN1; SMN2PTPN11 | |
| SCHEMBL30399768 | 0.84 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNASMN1; SMN2PTPN11 | |
| SCHEMBL20292779 | 0.80 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1LMNASMN1; SMN2PTPN11 | |
| SCHEMBL30349392 | 0.79 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1LMNASMN1; SMN2EGFR | |
| SCHEMBL25209802 | 0.79 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1LMNASMN1; SMN2EGFR | |
| SCHEMBL16854347 | 0.79 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1PTPN11ABL1 | |
| SCHEMBL30542285 | 0.78 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1LMNASMN1; SMN2PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415817-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AS DYRK1A INHIBITORS | BioSplice Therapeutics, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064349-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AS DYRK1A INHIBITORS | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |