Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | PRNP | P04156 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12210462 | 0.93 | KDM4E (0.62) | CDK1CYP2D6CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL16261305 | 0.85 | CDK1 (0.53) | CDK1CYP2D6CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL1612342 | 0.82 | CYP2D6 (0.67) | CYP2D6CYP1A2CYP3A4HSD17B10LMNA | |
| SCHEMBL7102744 | 0.81 | CYP2D6 (0.50) | CDK1CYP2D6CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL2521033 | 0.80 | CYP3A4 (0.53) | CYP2D6CYP1A2CYP3A4FERMT2ACHE | |
| SCHEMBL1147366 | 0.78 | CDK1 (0.87) | CDK1CYP2D6CYP1A2HSD17B10LMNA | |
| SCHEMBL16261319 | 0.77 | KDM4E (0.56) | CDK1CYP2D6CYP1A2CYP3A4HSD17B10 | |
| Hydrochloric Acid SCHEMBL29695676 | 0.77 | CDK1 (0.85) | CDK1CYP2D6CYP1A2HSD17B10LMNA | |
| SCHEMBL15120920 | 0.77 | CDK1 (0.48) | CDK1CYP2D6CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL1147619 | 0.76 | CDK1 (0.87) | CDK1CYP2D6CYP1A2HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481543-B2 | Compounds for treating parasitic disease | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2013-07-09 | — | — | US | disclosed |
| US-8481543-B2 | Compounds for treating parasitic disease | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2013-07-09 | — | — | US | disclosed |
| US-8481543-B2 | Compounds for treating parasitic disease | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2013-07-09 | — | — | US | disclosed |
| US-20110251209-A1 | COMPOUNDS FOR TREATING PARASITIC DISEASE | OREGON HEALTH & SCIENCE UNIVERSITY | 2011-10-13 | — | — | US | disclosed |
| US-20110251209-A1 | COMPOUNDS FOR TREATING PARASITIC DISEASE | OREGON HEALTH & SCIENCE UNIVERSITY | 2011-10-13 | — | — | US | disclosed |
| US-20110251209-A1 | COMPOUNDS FOR TREATING PARASITIC DISEASE | OREGON HEALTH & SCIENCE UNIVERSITY | 2011-10-13 | — | — | US | disclosed |
| WO-2010059633-A2 | COMPOUNDS FOR TREATING PARASITIC DISEASE | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010059633-A2 | COMPOUNDS FOR TREATING PARASITIC DISEASE | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251209-A1 | COMPOUNDS FOR TREATING PARASITIC DISEASE | EPX, CFTR, TERT | CDK1 3732/4885CYP2D6 449/4885CYP1A2 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.