SCHEMBL25210567

SCHEMBL25210567

O=C(/C=C/c1ccc(OCc2ccccc2)cc1)c1ccc(N2CCC(O)CC2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCG2 Q9UNQ0 2/20 0.65
▸ MAOB P27338 4/20 0.63
▸ GSK3B P49841 2/20 0.53
▸ BACE1 P56817 2/20 0.53
▸ MAPT P10636 4/20 0.53
▸ KMT2A Q03164 3/20 0.53
▸ NPC1 O15118 3/20 0.53
▸ RAB9A P51151 3/20 0.53
▸ MEN1 O00255 2/20 0.53
▸ SMN1; SMN2 Q16637 2/20 0.53
▸ L3MBTL1 Q9Y468 2/20 0.53
▸ ALDH1A1 P00352 1/20 0.53
▸ SLC5A1 P13866 1/20 0.52
▸ SLC5A2 P31639 1/20 0.52
▸ CTSL P07711 1/20 0.51
▸ CTSB P07858 1/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ TP53 P04637 1/20 0.51
▸ MAOA P21397 1/20 0.49
▸ APP P05067 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25206148 1.00 ABCG2 (0.65) ABCG2MAOBGSK3BBACE1MAPT
SCHEMBL25198427 0.86 MAOB (0.51) ABCG2MAOBMAPTKMT2ANPC1
SCHEMBL25225683 0.86 CTSL (0.47) ABCG2MAOBMAPTKMT2ANPC1
SCHEMBL25278953 0.85 MAOB (0.61) ABCG2MAOBMAPTKMT2ANPC1
SCHEMBL25199591 0.85 MAOB (0.61) ABCG2MAOBMAPTKMT2ANPC1
SCHEMBL25202010 0.84 MAOB (0.71) MAOBMAPTKMT2ANPC1RAB9A
SCHEMBL25203870 0.84 MAOB (0.71) MAOBMAPTKMT2ANPC1RAB9A
SCHEMBL25195607 0.84 APP (0.59) MAPTKMT2ANPC1RAB9AMEN1
SCHEMBL17888549 0.83 RAB9A (0.68) MAPTNPC1RAB9AALDH1A1KDM4E
SCHEMBL25193762 0.82 F3 (0.64) MAOBMAPTKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885MAOB 1004/4885GSK3B 193/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAOB 2435/4885GSK3B 1167/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAOB 2435/4885GSK3B 1167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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