Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25211230 | 1.00 | LMNA (0.46) | LMNATHRBUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL19859887 | 1.00 | LMNA (0.46) | LMNATHRBUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL3411530 | 0.97 | — | — | |
| Ethylene Glycol SCHEMBL2402471 | 0.95 | THRB (0.48) | LMNATHRBUSP2CYP3A4SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL14919937 | 0.95 | THRB (0.48) | LMNATHRBUSP2CYP3A4SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL12493198 | 0.95 | THRB (0.48) | LMNATHRBUSP2CYP3A4SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL18188061 | 0.95 | THRB (0.48) | LMNATHRBUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL9284115 | 0.95 | LMNA (0.42) | LMNATHRBUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL1358706 | 0.89 | — | — | |
| SCHEMBL25389134 | 0.86 | THRB (0.59) | LMNATHRBUSP2CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102364-A1 | ANTIVIRAL COMPOUNDS, COMPOSITIONS AND USES THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2023-06-08 | — | — | WO | disclosed |