Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19859887 | 0.95 | LMNA (0.46) | LMNATHRBACACBACACAUSP2 | |
| SCHEMBL25211230 | 0.95 | LMNA (0.46) | LMNATHRBACACBACACAUSP2 | |
| SCHEMBL25211485 | 0.95 | LMNA (0.46) | LMNATHRBACACBACACAUSP2 | |
| SCHEMBL3411530 | 0.93 | — | — | |
| Ethylene Glycol SCHEMBL2402471 | 0.91 | THRB (0.48) | LMNATHRBACACBACACAUSP2 | |
| Ethylene Glycol SCHEMBL12493198 | 0.91 | THRB (0.48) | LMNATHRBACACBACACAUSP2 | |
| Ethylene Glycol SCHEMBL18188061 | 0.91 | THRB (0.48) | LMNATHRBACACBACACAUSP2 | |
| Ethylene Glycol SCHEMBL14919937 | 0.91 | THRB (0.48) | LMNATHRBACACBACACAUSP2 | |
| SCHEMBL1358706 | 0.85 | — | — | |
| SCHEMBL28656406 | 0.83 | THRB (0.43) | THRBACACBACACAFOLH1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485874-B1 | Transducer for immunosensor and its method of production | HOFFMANN LA ROCHE (CH) | 1995-09-20 | — | — | EP | disclosed |
| EP-0485874-A2 | Transducer for immunosensor and its method of production | F. HOFFMANN-LA ROCHE AG (CH) | 1992-05-20 | — | — | EP | disclosed |