Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL18188061 | 1.00 | THRB (0.48) | THRBLMNAUSP2CYP3A4SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL2402471 | 1.00 | THRB (0.48) | THRBLMNAUSP2CYP3A4SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL12493198 | 1.00 | THRB (0.48) | THRBLMNAUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL25211485 | 0.95 | LMNA (0.46) | THRBLMNAUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL19859887 | 0.95 | LMNA (0.46) | THRBLMNAUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL25211230 | 0.95 | LMNA (0.46) | THRBLMNAUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL3411530 | 0.93 | — | — | |
| SCHEMBL9284115 | 0.91 | LMNA (0.42) | THRBLMNAUSP2CYP3A4SMN1; SMN2 | |
| Acetic Acid SCHEMBL4340902 | 0.88 | ACACB (0.42) | THRBLMNAUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL1358706 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773958-B1 | A METHOD OF IDENTIFYING AN ANALYTE IN A BIOLOGICAL SAMPLE | UNIV CAPE TOWN (ZA) | 2017-11-29 | — | — | EP | disclosed |
| US-9518986-B2 | Method of detecting and/or quantifying an analyte in a biological sample | UNIVERSITY OF CAPE TOWN (ZA) | 2016-12-13 | — | — | US | disclosed |
| US-20140302492-A1 | METHOD OF DETECTING AND/OR QUALIFYING AN ANALYTE IN A BIOLOGICAL SAMPLE | UNIVERSITY OF CAPE TOWN (ZA) | 2014-10-09 | — | — | US | disclosed |
| EP-2773958-A1 | A METHOD OF DETECTING AND/OR QUANTIFYING AN ANALYTE IN A BIOLOGICAL SAMPLE | University of Cape Town (ZA) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013065016-A1 | A METHOD OF DETECTING AND/OR QUANTIFYING AN ANALYTE IN A BIOLOGICAL SAMPLE | UNIVERSITY OF CAPE TOWN (ZA) | 2013-05-10 | — | — | WO | disclosed |