SCHEMBL25211503

SCHEMBL25211503

CN(CCCC(=O)OCc1ccccc1)C(=O)OC(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.48
ALDH1A1 P00352 3/20 0.44
MAPK1 P28482 1/20 0.44
ALOX5 P09917 1/20 0.43
LMNA P02545 1/20 0.41
GBA1 P04062 1/20 0.41
SYK P43405 1/20 0.40
LTA4H P09960 1/20 0.40
HTR2C P28335 1/20 0.40
SLC6A4 P31645 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28956076 0.92 L3MBTL1 (0.47) L3MBTL1ALDH1A1MAPK1LMNAGBA1
SCHEMBL16466428 0.90 L3MBTL1 (0.46) L3MBTL1ALDH1A1MAPK1ALOX5SYK
SCHEMBL31170532 0.88 L3MBTL1 (0.49) L3MBTL1ALDH1A1MAPK1ALOX5LMNA
SCHEMBL18686281 0.85 L3MBTL1 (0.45) L3MBTL1ALDH1A1MAPK1LMNASYK
SCHEMBL7775544 0.85 L3MBTL1 (0.50) L3MBTL1ALDH1A1MAPK1GBA1SYK
SCHEMBL30315266 0.85 L3MBTL1 (0.44) L3MBTL1ALDH1A1MAPK1LMNAGBA1
SCHEMBL7703626 0.84 ALDH1A1 (0.49) L3MBTL1ALDH1A1MAPK1LMNASYK
SCHEMBL30976198 0.84 L3MBTL1 (0.40) L3MBTL1ALDH1A1MAPTHPGD
SCHEMBL1455946 0.84 L3MBTL1 (0.45) L3MBTL1ALDH1A1MAPK1GBA1SYK
SCHEMBL21998139 0.84 L3MBTL1 (0.56) L3MBTL1ALDH1A1LMNASYKHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4566608-A2 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2025-06-11 EP disclosed
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2025-06-05 US disclosed
EP-4440702-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 EP disclosed
EP-4445900-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 EP disclosed
US-12187753-B2 Therapeutics compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2025-01-07 US disclosed
EP-4445900-A2 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2024-10-16 EP disclosed
EP-4440702-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2024-10-09 EP disclosed
US-20240132527-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2024-04-25 US disclosed
US-11787825-B2 Therapeutic compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2023-10-17 US disclosed
US-11787825-B2 Therapeutic compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2023-10-17 US disclosed
US-20230203069-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2023-06-29 US disclosed
US-20230203069-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2023-06-29 US disclosed
WO-2023102239-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2023-06-08 WO disclosed
WO-2023102239-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2023-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION CD4, HAVCR2, MAVS L3MBTL1 1204/4885ALDH1A1 1512/4885MAPK1 4303/4885
US-11787825-B2 Therapeutic compounds for HIV virus infection HAVCR2, MAVS, CD4 L3MBTL1 1303/4885ALDH1A1 1718/4885MAPK1 4199/4885
US-12187753-B2 Therapeutics compounds for HIV virus infection CD4, HAVCR2, MAVS L3MBTL1 1204/4885ALDH1A1 1512/4885MAPK1 4303/4885
US-20230203069-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION HAVCR2, MAVS, CD4 L3MBTL1 1303/4885ALDH1A1 1718/4885MAPK1 4199/4885
US-20240132527-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION CD4, HAVCR2, MAVS L3MBTL1 1204/4885ALDH1A1 1512/4885MAPK1 4303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.