SCHEMBL25212

SCHEMBL25212

C/C(=C\C=O)CC1=CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
ALOX15 P16050 1/20 0.41
TAAR1 Q96RJ0 1/20 0.37
TSHR P16473 3/20 0.36
CXCR3 P49682 1/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
HSD17B10 Q99714 1/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
HPGD P15428 1/20 0.35
PKM P14618 1/20 0.35
TRPV1 Q8NER1 1/20 0.35
GSTP1 P09211 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25214 1.00 ALDH1A1 (0.41) ALDH1A1ALOX15TAAR1TSHRCXCR3
SCHEMBL27927911 0.82 ALDH1A1 (0.39) ALDH1A1ALOX15TAAR1TSHRCXCR3
SCHEMBL30603 0.77 ALDH1A1 (0.36) ALDH1A1ALOX15TAAR1TSHRCXCR3
SCHEMBL24784 0.77 ALDH1A1 (0.36) ALDH1A1ALOX15TAAR1TSHRCXCR3
SCHEMBL4635955 0.76 ALDH1A1 (0.40) ALDH1A1ALOX15TAAR1TSHRCXCR3
SCHEMBL722436 0.76 ALDH1A1 (0.44) ALDH1A1ALOX15TAAR1TSHRSMN1; SMN2
SCHEMBL9630730 0.76 GSTP1 (0.33) ALDH1A1ALOX15TAAR1TSHRCXCR3
SCHEMBL66707 0.75 ALDH1A1 (0.42) ALDH1A1ALOX15CXCR3SMN1; SMN2HSD17B10
SCHEMBL7991192 0.74 CXCR3 (0.42) ALDH1A1ALOX15CXCR3SMN1; SMN2HSD17B10
SCHEMBL23726 0.73 ALDH1A1 (0.41) ALDH1A1ALOX15TAAR1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2609184-B1 PERFUMERY COMPOSITIONS AND SYNTHESIS OF A ODORANT VAZE KEDAR RAMESH (IN) 2017-02-15 EP claimed
EP-2609184-A1 SYNTHESIS OF A NOVEL ODORANT Vaze, Kedar Ramesh (IN) 2013-07-03 EP claimed
US-20130157923-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2013-06-20 US claimed
WO-2012025934-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2012-03-01 WO claimed
US-9845443-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2017-12-19 US disclosed
US-9845443-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2017-12-19 US disclosed
US-9845443-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2017-12-19 US disclosed
EP-2609184-B1 PERFUMERY COMPOSITIONS AND SYNTHESIS OF A ODORANT VAZE KEDAR RAMESH (IN) 2017-02-15 EP disclosed
EP-2609184-B1 PERFUMERY COMPOSITIONS AND SYNTHESIS OF A ODORANT VAZE KEDAR RAMESH (IN) 2017-02-15 EP disclosed
US-20160024424-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2016-01-28 US disclosed
US-20160024424-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2016-01-28 US disclosed
US-20160024424-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2016-01-28 US disclosed
US-9187709-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2015-11-17 US disclosed
CN-103210074-A Synthesis of a novel odorant VAZE KEDAR RAMESH 2013-07-17 CN disclosed
EP-2609184-A1 SYNTHESIS OF A NOVEL ODORANT Vaze, Kedar Ramesh (IN) 2013-07-03 EP disclosed
US-20130157923-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2013-06-20 US disclosed
US-20130157923-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2013-06-20 US disclosed
US-20130157923-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2013-06-20 US disclosed
WO-2012025934-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2012-03-01 WO disclosed
WO-2012025934-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160024424-A1 SYNTHESIS OF A NOVEL ODORANT OR10J3, OR51E2, TAS2R10 ALDH1A1 1280/4885ALOX15 1505/4885TAAR1 156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.