SCHEMBL66707

SCHEMBL66707

C[C](C)CC1=CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.42
ALOX15 P16050 2/20 0.42
PKM P14618 1/20 0.41
CXCR3 P49682 2/20 0.40
SMN1; SMN2 Q16637 5/20 0.39
NPC1 O15118 5/20 0.39
RAB9A P51151 5/20 0.39
LMNA P02545 2/20 0.38
HTT P42858 2/20 0.38
HPGD P15428 2/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
ATM Q13315 1/20 0.38
HSD17B10 Q99714 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7991192 0.98 CXCR3 (0.42) ALDH1A1ALOX15PKMCXCR3SMN1; SMN2
SCHEMBL7994833 0.93
SCHEMBL4635955 0.83 ALDH1A1 (0.40) ALDH1A1ALOX15PKMCXCR3SMN1; SMN2
SCHEMBL722436 0.83 ALDH1A1 (0.44) ALDH1A1ALOX15PKMSMN1; SMN2NPC1
SCHEMBL27927911 0.81 ALDH1A1 (0.39) ALDH1A1ALOX15PKMCXCR3SMN1; SMN2
SCHEMBL6165925 0.77 ALDH1A1 (0.45) ALDH1A1ALOX15SMN1; SMN2NPC1RAB9A
SCHEMBL7776189 0.77 ALDH1A1 (0.40) ALDH1A1ALOX15SMN1; SMN2NPC1RAB9A
SCHEMBL24784 0.77 ALDH1A1 (0.36) ALDH1A1ALOX15PKMCXCR3SMN1; SMN2
SCHEMBL30603 0.77 ALDH1A1 (0.36) ALDH1A1ALOX15PKMCXCR3SMN1; SMN2
SCHEMBL3647069 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115340504-B Fluorene group-containing compound and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2024-06-21 CN disclosed
EP-2288340-B1 NANOPARTICLE FORMULATIONS AND USES THEREOF ABRAXIS BIOSCIENCE LLC (US) 2020-06-24 EP disclosed
EP-2416650-B1 NANOPARTICLE FORMULATIONS AND USES THEROF ABRAXIS BIOSCIENCE LLC (US) 2020-02-26 EP disclosed
US-10570431-B2 Compositions comprising a polypeptide having cellulolytic enhancing activity and a heterocyclic compound and uses thereof NOVOZYMES, INC. (US) 2020-02-25 US disclosed
US-20180363018-A1 Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Heterocyclic Compound And Uses Thereof NOVOZYMES, INC. (US) 2018-12-20 US disclosed
US-20180289620-A1 NANOPARTICLE FORMULATIONS AND USES THEREOF ABRAXIS BIOSCIENCE, LLC 2018-10-11 US disclosed
US-10087478-B2 Compositions comprising a polypeptide having cellulolytic enhancing activity and a nitrogen-containing compound and uses thereof NOVOZYMES, INC. (US) 2018-10-02 US disclosed
US-10041101-B2 Compositions comprising a polypeptide having cellulolytic enhancing activity and a heterocyclic compound and uses thereof NOVOZYMES, INC. (US) 2018-08-07 US disclosed
EP-2603594-B1 COMPOSITIONS COMPRISING A POLYPEPTIDE HAVING CELLULOLYTIC ENHANCING ACTIVITY AND A BICYCLIC COMPOUND AND USES THEREOF NOVOZYMES INC (US) 2018-04-25 EP disclosed
EP-2603598-B1 COMPOSITIONS COMPRISING A GH61 POLYPEPTIDE HAVING CELLULOLYTIC ENHANCING ACTIVITY AND A QUINONE COMPOUND AND USES THEREOF NOVOZYMES INC (US) 2018-04-18 EP disclosed
WO-2009126938-A1 NANOPARTICLE FORMULATIONS AND USES THEREOF ABRAXIS BIOSCIENCES, LLC (US) 2009-10-15 WO disclosed
WO-2009126401-A1 COMPOSITIONS OF HYDROPHOBIC TAXANE DERIVATIVES AND USES THEREOF ABRAXIS BIOSCIENCE, LLC (US) 2009-10-15 WO disclosed
WO-2009115572-A2 NOVEL HETEROCYCLIC COMPOUNDS AND USES THEROF NOVARTIS AG (CH) 2009-09-24 WO disclosed
WO-2009042694-A1 (3-HYDROXY-4-AMINO-BUTAN-2-YL) -3- (2-THIAZOL-2-YL-PYRROLIDINE-1-CARBONYL) BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BETA-SECRETASE INHIBITORS FOR TREATING COMENTIS, INC. (US) 2009-04-02 WO disclosed
WO-2008155727-A1 PLATINUM (IV) COMPLEXES PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2008-12-24 WO disclosed
CN-101145514-A Method of forming fine pattern of semiconductor device HYNIX SEMICONDUCTOR INC (KR) 2008-03-19 CN disclosed
CN-101145515-A Method for forming a fine pattern of a semiconductor device HYNIX SEMICONDUCTOR INC (KR) 2008-03-19 CN disclosed
US-6277790-B1 APPLYING PLANTS, SEEDS, SOILS OR ENVIRONMENT BASF AKTIENGESELLSCHAFT (DE) 2001-08-21 US disclosed
EP-1003741-A1 SUBSTITUTED HERBICIDE TETRAZOLINONECARBOXYLIC ACID AMIDES BASF AKTIENGESELLSCHAFT (DE) 2000-05-31 EP disclosed
WO-1999007702-A1 SUBSTITUTED HERBICIDE TETRAZOLINONECARBOXYLIC ACID AMIDES BASF AKTIENGESELLSCHAFT (DE) 1999-02-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180289620-A1 NANOPARTICLE FORMULATIONS AND USES THEREOF ABCB1, SLC47A1, ABCC1 ALDH1A1 1501/4885ALOX15 3586/4885PKM 3884/4885
US-10570431-B2 Compositions comprising a polypeptide having cellulolytic enhancing activity and a heterocyclic compound and uses thereof CEL, VIP, CTRC ALDH1A1 4339/4885ALOX15 738/4885PKM 1703/4885
US-20180363018-A1 Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Heterocyclic Compound And Uses Thereof CEL, VIP, CTRC ALDH1A1 4339/4885ALOX15 738/4885PKM 1703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.