Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30658006 | 0.89 | IL1B (0.40) | HCAR1GPR119MAPTKDM4ETHRB | |
| SCHEMBL26654138 | 0.89 | IL1B (0.40) | HCAR1GPR119MAPTKDM4ETHRB | |
| SCHEMBL22802021 | 0.82 | HCAR1 (0.47) | HCAR1GPR119MAPTKDM4ETHRB | |
| SCHEMBL34469726 | 0.81 | OXTR (0.36) | HCAR1GPR119 | |
| SCHEMBL5253861 | 0.78 | STS (0.47) | HCAR1GPR119MAPTKDM4ETHRB | |
| SCHEMBL4990941 | 0.78 | STS (0.47) | HCAR1GPR119MAPTKDM4ETHRB | |
| SCHEMBL23442868 | 0.77 | HCAR1 (0.47) | HCAR1GPR119 | |
| SCHEMBL25151139 | 0.77 | HCAR1 (0.46) | HCAR1GPR119MAPTSTSNPC1 | |
| SCHEMBL30658018 | 0.77 | MAPT (0.44) | GPR119MAPTKDM4ETHRBSTS | |
| SCHEMBL26654058 | 0.77 | MAPT (0.44) | GPR119MAPTKDM4ETHRBSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |