Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.59 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.59 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20660318 | 0.93 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1SMN1; SMN2LMNA | |
| SCHEMBL8396587 | 0.88 | LMNA (0.63) | TPSAB1TPSD1TPSG1SMN1; SMN2LMNA | |
| SCHEMBL25679047 | 0.88 | TPSAB1 (0.56) | TPSAB1TPSD1TPSG1SMN1; SMN2LMNA | |
| SCHEMBL21248842 | 0.87 | LMNA (0.56) | TPSAB1TPSD1TPSG1SMN1; SMN2LMNA | |
| SCHEMBL1240612 | 0.87 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1SMN1; SMN2LMNA | |
| SCHEMBL20782479 | 0.86 | KDM4E (0.58) | TPSAB1TPSD1TPSG1SMN1; SMN2HTT | |
| SCHEMBL16528456 | 0.86 | MEN1 (0.50) | TPSAB1TPSD1TPSG1SMN1; SMN2LMNA | |
| SCHEMBL8396013 | 0.85 | LMNA (0.60) | TPSAB1TPSD1TPSG1SMN1; SMN2LMNA | |
| SCHEMBL8391394 | 0.85 | MEN1 (0.63) | TPSAB1TPSD1TPSG1SMN1; SMN2LMNA | |
| SCHEMBL27358592 | 0.85 | ACHE (0.58) | TPSAB1TPSD1TPSG1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183239-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF | ABBVIE INC (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183239-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF | ENPP1, ENPP3, STING1 | TPSAB1 1238/4885TPSD1 2690/4885TPSG1 937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.