Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESRRG | P62508 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL26627227 | 0.83 | HIF1A (0.52) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL16935751 | 0.82 | HIF1A (0.50) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL15939727 | 0.82 | HIF1A (0.50) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL26627221 | 0.82 | HIF1A (0.50) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL16935729 | 0.80 | HIF1A (0.48) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Bromide SCHEMBL20210981 | 0.80 | HIF1A (0.48) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL25206160 | 0.77 | HIF1A (0.48) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL25219263 | 0.77 | CHRNA7 (0.50) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL25203803 | 0.73 | HTR1B (0.50) | HIF1ACHRNA7 | |
| SCHEMBL25755569 | 0.73 | MGMT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626900-A1 | PORPHYRIN AND PHOSPHONIUM-PORPHYRIN BASED COMPOUNDS FOR PHOTODYNAMIC THERAPY AND DIAGNOSTICS | RMW Cho Group Limited (HK) | 2025-10-08 | — | — | EP | disclosed |
| US-20250177533-A1 | PHOTODYNAMIC THERAPY AND DIAGNOSIS | Invion Limited (AU) | 2025-06-05 | — | — | US | disclosed |
| US-20250115633-A1 | PHOTODYNAMIC THERAPY AND DIAGNOSIS | Invion Limited (AU) | 2025-04-10 | — | — | US | disclosed |
| EP-4436971-A1 | PHOTODYNAMIC THERAPY AND DIAGNOSIS | RMW Cho Group Limited (HK) | 2024-10-02 | — | — | EP | disclosed |
| EP-4436972-A1 | PHOTODYNAMIC THERAPY AND DIAGNOSIS | RMW Cho Group Limited (HK) | 2024-10-02 | — | — | EP | disclosed |
| CN-118679165-A | Photodynamic therapy and diagnosis | RMW曹氏集团有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-118679164-A | Photodynamic therapy and diagnosis | RMW曹氏集团有限公司 | 2024-09-20 | — | — | CN | disclosed |
| WO-2024115524-A1 | PORPHYRIN AND PHOSPHONIUM-PORPHYRIN BASED COMPOUNDS FOR PHOTODYNAMIC THERAPY AND DIAGNOSTICS | RMW CHO GROUP LIMITED (CN) | 2024-06-06 | — | — | WO | disclosed |
| WO-2023094679-A1 | PHOTODYNAMIC THERAPY AND DIAGNOSIS | RMW CHO GROUP LIMITED (CN) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023094677-A1 | PHOTODYNAMIC THERAPY AND DIAGNOSIS | RMW CHO GROUP LIMITED (CN) | 2023-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115633-A1 | PHOTODYNAMIC THERAPY AND DIAGNOSIS | TPD52L2, CPNE4, CCNE2 | HIF1A 1063/4885CHRNA7 4132/4885ALDH1A1 704/4885 |
| US-20250177533-A1 | PHOTODYNAMIC THERAPY AND DIAGNOSIS | PPOX, PPIF, ALAD | HIF1A 700/4885CHRNA7 4862/4885ALDH1A1 618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.