SCHEMBL2522495

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2522501	1.00	CDK9 (0.47)	CDK9CCNT1RORCPPARGMEN1
	SCHEMBL2523997	0.84	CCNT1 (0.37)	CDK9CCNT1MEN1KMT2ARAB9A
	SCHEMBL2523991	0.84	CCNT1 (0.37)	CDK9CCNT1MEN1KMT2ARAB9A
	SCHEMBL2506781	0.81	KDM4E (0.49)	CDK9CCNT1RORCMEN1KMT2A
	SCHEMBL2506784	0.81	KDM4E (0.49)	CDK9CCNT1RORCMEN1KMT2A
	SCHEMBL19746393	0.78	NPC1 (0.46)	CDK9CCNT1RORCPPARGRAB9A
	SCHEMBL9703865	0.77	SLC6A4 (0.60)	RAB9AL3MBTL1KDM4EALDH1A1MAPT
	SCHEMBL18866863	0.76	SLC6A3 (0.42)	RAB9ASLC6A3KDM4EALDH1A1GAA
	SCHEMBL2521074	0.75	CCNT1 (0.50)	CDK9CCNT1RORCPPARG
	SCHEMBL18866894	0.75	CDK9 (0.50)	CDK9CCNT1RORCPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.